Electrospinning of hyaluronan/polyvinyl alcohol in presence of in-situ silver nanoparticles: Preparation and characterization

被引：45

作者：

Abdel-Mohsen, A. M. ^{[1
,2
]}

Pavlinak, D. ^{[3
]}

Cilekova, M. ^{[4
]}

Lepcio, P. ^{[1
]}

Abdel-Rahman, R. M. ^{[1
]}

Jancar, J. ^{[1
,4
]}

机构：

[1] Brno Univ Technol, CEITEC Cent European Inst Technol, Purkynova 123, Brno, Czech Republic

[2] Natl Res Ctr, Text Res Div, Pretreatment & Finishing Cellulos Fibers, Cairo, Egypt

[3] Masaryk Univ, Dept Phys Elect, Brno, Czech Republic

[4] Brno Univ Technol, Fac Chem, Inst Mat Chem, Purkynova 118, Brno 61200, Czech Republic

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2019年 / 139卷

关键词：

Nanocomposite; Electrospinning; Nanofiber; in-situ AgNPs; Hyaluronan; COMPOSITE NANOFIBERS; CHITOSAN NANOFIBERS; DRUG-DELIVERY; CROSS-LINKING; GOLD; REGENERATION; FABRICATION; GENERATION; HYDROGEL; GROWTH;

D O I：

10.1016/j.ijbiomac.2019.07.205

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Novel nanofibers mats were fabricated by electrospinning of polyvinyl alcohol/hyaluronan (PVA/HA) solutions in the presence of silver nanoparticles (AgNPs). The AgNPs were synthesized by in-situ chemical reduction of silver ions (Ag+) using HA as a reducing and stabilizing agent. Narrow size distribution and spherical shape of AgNPs were achieved by optimizing the initial silver nitrate concentration (0.01 to 1 M) and reaction time (10-60 min). HA-AgNPs nanocomposite and PVA/HA-AgNPs nanofibrous mats were fabricated by electrospinning technique from aqueous solution containing a different mass ratio of PVA and HA-AgNPs and characterized by UV/Vis spectroscopy, SEM, TEM, DLS, XRD, TGA, and ATR-FTIR. Mechanical and rheological properties were also investigated and discussed. The novel nanofibrous mats show great potential in skin regeneration and drug carrier applications. (C) 2019 Elsevier B.V. All rights reserved.

引用

页码：730 / 739

页数：10

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