Comparison of chiral thiazolium and triazolium salts as asymmetric catalysts for the benzoin condensation

被引：199

作者：

Knight, RL ^{[1
]}

Leeper, FJ ^{[1
]}

机构：

[1] Univ Cambridge, Chem Lab, Cambridge CB2 1EW, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1998年 / 12期

关键词：

D O I：

10.1039/a803635g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chiral bicyclic 1,2,4-triazolium salts having a defined face of the heterocyclic ring hindered have been synthesised and they catalyse the benzoin condensation in good yield;:the enantiomeric excesses obtained (up to 80%) are much better than with closely related thiazolium salts and the opposite enantiomer of benzoin predominates.

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页码：1891 / 1893

页数：3

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