A facile four-component tandem protocol for the synthesis of novel 2,6-diaryl-2,3-dihydro-1H-pyridin-4-ones

被引：19

作者：

Devi, Natarajan Savitha ^{[1
]}

Perumal, Subbu ^{[1
]}

机构：

[1] Madurai Kamaraj Univ, Sch Chem, Dept Organ Chem, Madurai 625021, Tamil Nadu, India

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 32期

关键词：

pyridinone; 1-(arylsulfinyl)propan-2-one; Mannich; elimination; tandem;

D O I：

10.1016/j.tetlet.2007.06.024

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot, four-component reaction of 1-(phenylsulfinyl)- or 1-(4-chlorophenylsulfinyl)propan-2-one, aromatic aldehydes and ammonium acetate in a 1:2:1 molar ratio affords a series of new 2,6-diaryl-2,3-dihydro-1H-pyridin-4-ones. This reaction proceeds presumably via a double Mannich reaction-elimination tandem sequence. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：5627 / 5629

页数：3

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