Atypical presentation of acute coronary syndrome: A significant independent predictor of in-hospital mortality

被引:56
作者
El-Menyar, Ayman [1 ,2 ]
Zubaid, Mohammad [3 ]
Sulaiman, Kadhim [4 ]
AlMahmeed, Wael [5 ]
Singh, Rajvir [6 ]
Alsheikh-Ali, Alawi A. [7 ]
Al Suwaidi, Jassim [1 ,2 ]
机构
[1] Hamad Med Corp, Dept Cardiol, Doha, Qatar
[2] Weill Cornell Med Sch, Doha, Qatar
[3] Kuwait Univ, Fac Med, Dept Med, Safat 13060, Kuwait
[4] Royal Hosp, Dept Cardiol, Muscat, Oman
[5] Sheikh Khalifa Med City, Abu Dhabi, U Arab Emirates
[6] Hamad Med Corp, Med Res Ctr, Doha, Qatar
[7] Tufts Med Ctr, Tufts Clin & Translat Sci Inst, Boston, MA USA
关键词
Typical angina; Atypical chest pain; Dyspnea; Acute coronary syndrome; ACUTE MYOCARDIAL-INFARCTION; CHEST-PAIN; GLOBAL REGISTRY; SYMPTOM PRESENTATION; ANGINA-PECTORIS; OUTCOMES; EVENTS; MANAGEMENT; PROGNOSIS; GRACE;
D O I
10.1016/j.jjcc.2010.11.008
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Patients with acute coronary syndrome (ACS) frequently present with typical chest pain; however a considerable proportion may present with atypical symptoms. Objective: The purpose of this study was to evaluate the prognostic value of different presenting symptoms in ACS patients. Methods: Over a 5-month period in 2007, 6704 consecutive patients presenting with ACS were enrolled and categorized into three groups according to their presenting symptom (typical chest pain, atypical chest pain, and dyspnea). Data were collected from a prospective, multicenter, multinational, observational study from 6 countries. The baseline characteristics, therapy, and in-hospital outcomes were analyzed and compared in the three groups. (C) 2011 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:165 / 171
页数:7
相关论文
共 24 条
[1]   Rationale and design of the GRACE (Global Registry of Acute Coronary Events) Project:: A multinational registry of patients hospitalized with acute coronary syndromes [J].
Agnelli, G ;
Avezum, A ;
Brieger, D ;
Budaj, A ;
Cannon, CP ;
Goldberg, RJ ;
Goodman, S ;
Gulba, DC ;
Granger, C ;
Kennelly, BM ;
Gurfinkel, E ;
López-Sendón, J ;
Klein, W ;
Montalescot, G ;
Van de Werf, F .
AMERICAN HEART JOURNAL, 2001, 141 (02) :190-199
[2]   Physiological and anatomical bases for sex differences in pain and nausea as presenting symptoms of acute coronary syndromes [J].
Arslanian-Engoren, Cynthia ;
Engoren, Milo .
HEART & LUNG, 2010, 39 (05) :386-393
[3]   Acute coronary syndromes without chest pain, an underdiagnosed and undertreated high-risk group - Insights from the Global Registry of Acute Coronary Events [J].
Brieger, D ;
Eagle, KA ;
Goodman, SG ;
Steg, PG ;
Budaj, A ;
White, K ;
Montalescot, G .
CHEST, 2004, 126 (02) :461-469
[4]   American College of Cardiology key data elements and definitions for measuring the clinical management and outcomes of patients with acute coronary syndromes - A report of the American College of Cardiology Task Force on Clinical Data Standards (Acute Coronary Syndromes Writing Committee) [J].
Cannon, CP ;
Battler, A ;
Brindis, RG ;
Cox, JL ;
Ellis, SG ;
Every, NR ;
Flaherty, JT ;
Harrington, RA ;
Krumholz, HM ;
Simoons, ML ;
Van de Werf, FJJ ;
Weintraub, WS ;
Mitchell, KR ;
Morrisson, SL ;
Brandis, RG ;
Anderson, HV ;
Cannom, DS ;
Chitwood, WR ;
Cigarroa, JE ;
Collins-Nakai, RL ;
Ellis, SG ;
Gibbons, RJ ;
Grover, FL ;
Heidenreich, PA ;
Khandheria, BK ;
Knoebel, SB ;
Krumholz, HL ;
Malenka, DJ ;
Mark, DB ;
McKay, CR ;
Passamani, ER ;
Radford, MJ ;
Riner, RN ;
Schwartz, JB ;
Shaw, RE ;
Shemin, RJ ;
Van Fossen, DB ;
Verrier, ED ;
Watkins, MW ;
Phoubandith, DR ;
Furnelli, T .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2001, 38 (07) :2114-2130
[5]   Prevalence, clinical characteristics, and mortality among patients with myocardial infarction presenting without chest pain [J].
Canto, JG ;
Shlipak, MG ;
Rogers, WJ ;
Malmgren, JA ;
Frederick, PD ;
Lambrew, CT ;
Ornato, JP ;
Barron, HV ;
Kiefe, CI .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2000, 283 (24) :3223-3229
[6]   Atypical presentations among Medicare beneficiaries with unstable angina pectoris [J].
Canto, JG ;
Fincher, C ;
Kiefe, CI ;
Allison, JJ ;
Li, Q ;
Funkhouser, E ;
Centor, RM ;
Selker, HP ;
Weissman, NW .
AMERICAN JOURNAL OF CARDIOLOGY, 2002, 90 (03) :248-253
[7]   Symptom presentation of women with acute coronary syndromes - Myth vs reality [J].
Canto, John G. ;
Goldberg, Robert J. ;
Hand, Mary M. ;
Bonow, Robert O. ;
Sopko, George ;
Pepine, Carl J. ;
Long, Terry .
ARCHIVES OF INTERNAL MEDICINE, 2007, 167 (22) :2405-2413
[8]   EFFECT ON OUTCOME OF THE PRESENCE OR ABSENCE OF CHEST PAIN AT INITIATION OF RECOMBINANT TISSUE-PLASMINOGEN ACTIVATOR THERAPY IN ACUTE MYOCARDIAL-INFARCTION [J].
COX, DA ;
ROGERS, WJ ;
AGUIRRE, FV ;
FORMAN, S ;
SOLOMON, R ;
ZARET, BL .
AMERICAN JOURNAL OF CARDIOLOGY, 1994, 73 (11) :729-736
[9]   Symptom presentation of acute myocardial infarction: Influence of sex, age, and risk factors [J].
Culic, V ;
Eterovic, D ;
Miric, D ;
Silic, N .
AMERICAN HEART JOURNAL, 2002, 144 (06) :1012-1017
[10]   Atypical presentation and unrecognized myocardial infarction [J].
Culic, Viktor .
EUROPEAN HEART JOURNAL, 2006, 27 (21) :2607-2607