REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-5-(INDOL-3-YL- AND-2-YL)PYRROLIDIN-2-ONES FROM AVAILABLE REAGENTS

被引：13
|
作者：
Sadovoy, A. V. [1 ]
Kovrov, A. E. [1 ]
Golubeva, G. A. [1 ]
Sviridova, L. A. [1 ]
机构：
[1] Moscow MV Lomonosov State Univ, Moscow 117911, Russia
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2011年 / 46卷 / 10期
关键词：
1-alkyl-5-hydroxypyrrolidin-2-ones; 1-alkyl-5-indolylpyrrolidin-2-ones; indoles; amido-alkylation; DERIVATIVES;
D O I：
10.1007/s10593-011-0655-x
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reaction under mild conditions of 1-alkyl-5-hydroxypyrrolidin-2-ones with different indoles having a free 3 position leads exclusively to 1-alkyl-5-(indol-3-yl)pyrrolidin-2-ones but if position 3 is occupied to 1-alkyl-5-(indol-2-yl)pyrrolidin-2-ones.
引用
收藏
页码：1215 / 1223
页数：9
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