(Eco)toxicological maps: A new risk assessment method integrating traditional and in silico tools and its application in the Ledra River (Italy)

被引：12

作者：

Raitano, Giuseppa ^{[1
]}

Goi, Daniele ^{[2
]}

Pieri, Valentina ^{[3
]}

Passoni, Alice ^{[1
]}

Mattiussi, Michele ^{[4
]}

Lutman, Anna ^{[4
]}

Romeo, Isabella ^{[1
]}

Manganaro, Alberto ^{[1
]}

Marzo, Marco ^{[1
]}

Porta, Nicola ^{[1
]}

Baderna, Diego ^{[1
]}

Colombo, Andrea ^{[1
]}

Aneggi, Eleonora ^{[5
]}

Natolino, Fabrizio ^{[1
]}

Lodi, Marco ^{[1
]}

Bagnati, Renzo ^{[1
]}

Benfenati, Emilio ^{[1
]}

机构：

[1] IRCCS Ist Ric Farmacol Mario Negri, Dept Environm Hlth Sci, Milan, Italy

[2] Univ Udine, Polytech Dept Engn & Architecture, Udine, Italy

[3] Univ Parma, Dept Chem Sci Life Sci & Environm Sustainabil, Parma, Italy

[4] ARPA FVG, Palmanova, Italy

[5] Univ Udine, Dept Chem Phys & Environm, Udine, Italy

来源：

ENVIRONMENT INTERNATIONAL | 2018年 / 119卷

关键词：

(Q)SAR; Environmental risk assessment; CECs; Integrating strategy; Wastewater treatment plant; Human risk assessment; WATER TREATMENT PLANTS; URBAN WASTE-WATER; DRINKING-WATER; DAPHNIA-MAGNA; PHARMACEUTICALS; CARBAMAZEPINE; MODELS; QSAR; ACETAMINOPHEN; MECHANISMS;

D O I：

10.1016/j.envint.2018.06.035

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Contaminants giving rise to emerging concern like pharmaceuticals, personal care products, pesticides and Endocrine Disrupting Chemicals (EDCs) have been detected in wastewaters, as reported in the literature, but little is known about their (eco)toxicological effects and consequent human health impact. The present study aimed at overcoming this lack of information through the use of in silico methods integrated with traditional toxicological risk analysis. This is part of a pilot project involving the management of wastewater treatment plants in the Ledra River basin (Daly). We obtained data to work up a global risk assessment method combining the evaluations of health risks to humans and ecological receptors from chemical contaminants found in this specific area. The (eco)toxicological risk is expressed by a single numerical value, permitting the comparison of different sampling sites and the evaluation of future environmental and technical interventions.

引用

页码：275 / 286

页数：12

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