Capillary electrophoresis-mass spectrometry for the analysis of amino acids

被引：57

作者：

Desiderio, Claudia ^{[1
]}

Iavarone, Federica

Rossetti, Diana Valeria

Messana, Irene ^{[2
]}

Castagnola, Massimo ^{[1
]}

机构：

[1] Univ Cattolica Sacro Cuore, Ist Biochim & Biochim Clin, Ist Chim Riconoscimento Mol, Consiglio Nazl Ric,Fac Med, I-00168 Rome, Italy

[2] Univ Cagliari, Dipartimento Sci Applicate Biosistemi, Monserrato, CA, Italy

来源：

JOURNAL OF SEPARATION SCIENCE | 2010年 / 33卷 / 16期

关键词：

Amino acids; Capillary electrophoresis; Chiral separations; Mass spectrometry; FREE D-ASPARTATE; ELECTROSPRAY-IONIZATION; ASYMMETRIC DIMETHYLARGININE; QUANTITATIVE-ANALYSIS; D-SERINE; MS; CE; NEUROTRANSMITTERS; RACEMIZATION; PEPTIDES;

D O I：

10.1002/jssc.201000171

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

In this review, the recent contribution of CE-MS technology to the analysis of amino acids, as well as the advantages of the hyphenation and the technologies involved in the instrumental coupling are reported. Different sections are dedicated to the recent contributions of CE-MS to the analysis of protein amino acids and their post-translational modifications, such as phosphorylation and sulfation. CE-MS analysis of some amino acid derivatives, such as the free methylated-derivatives of arginine is also discussed. A section is specifically devoted to the CE-MS applications in the field of chiral separation of D-and L-amino acid enantiomers.

引用

页码：2385 / 2393

页数：9

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