Unusual synthesis of dihydropyrido[2,1-a]isoindolone derivatives by radical cyclization of enamides of Baylis-Hillman adducts

被引：22
|
作者：
Gowrisankar, Saravanan
Kim, Seong Jin
Lee, Ji-Eun
Kim, Jae Nyoung [1 ]
机构：
[1] Chonnam Natl Univ, Inst Basic Sci, Dept Chem, Kwangju 500757, South Korea
[2] Gyeongsang Natl Univ, Dept Chem BK21, Cent Instrument Facil, Chinju 660701, South Korea
来源：
TETRAHEDRON LETTERS | 2007年 / 48卷 / 25期
关键词：
dihydropyrido[2,1-a]isoindolone; radical cyclization; enamides; Baylis-Hillman adducts;
D O I：
10.1016/j.tetlet.2007.04.111
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
During the radical cyclization of enamide derivatives 4 we found unusual formation of dihydropyrido[2,1-a]isoindolone derivatives 5. The enamides were synthesized in four steps from the Baylis-Hillman adducts of ortho-bromobenzaldehydes. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码：4419 / 4422
页数：4
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