Unusual synthesis of dihydropyrido[2,1-a]isoindolone derivatives by radical cyclization of enamides of Baylis-Hillman adducts

被引：22

作者：

Gowrisankar, Saravanan

Kim, Seong Jin

Lee, Ji-Eun

Kim, Jae Nyoung ^{[1
]}

机构：

[1] Chonnam Natl Univ, Inst Basic Sci, Dept Chem, Kwangju 500757, South Korea

[2] Gyeongsang Natl Univ, Dept Chem BK21, Cent Instrument Facil, Chinju 660701, South Korea

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 25期

关键词：

dihydropyrido[2,1-a]isoindolone; radical cyclization; enamides; Baylis-Hillman adducts;

D O I：

10.1016/j.tetlet.2007.04.111

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

During the radical cyclization of enamide derivatives 4 we found unusual formation of dihydropyrido[2,1-a]isoindolone derivatives 5. The enamides were synthesized in four steps from the Baylis-Hillman adducts of ortho-bromobenzaldehydes. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：4419 / 4422

页数：4

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