Chemical composition and cytotoxicity of the essential oil from different parts of Datura metel L.

被引：12

作者：

Xue, Juan ^{[1
]}

Sun, Yichun ^{[1
]}

Wei, Qing ^{[1
]}

Wang, Changfu ^{[1
]}

Yang, Bingyou ^{[1
]}

Kuang, Haixue ^{[1
]}

Wang, Qiuhong ^{[1
]}

机构：

[1] Heilongjiang Univ Chinese Med, Key Lab Chinese Mat Med, Minist Educ, Harbin, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2016年 / 30卷 / 17期

关键词：

Datura metel L; essential oil; GC-MS; cytotoxicity; WITHANOLIDES; FLOWER;

D O I：

10.1080/14786419.2015.1088541

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The essential oil from different parts of Datura metel L. were extracted using hydrodistillation and GC-MS was used to analyse the essential oil. The main components of flowers were ketone (23.61%) and ethyl palmitate (15.84%). The main components of leaves were ketone (18.84%) and phytol (18.71%). Ketone (39.45%) and phytol (31.32%) were the major components of petioles. Palmitic acid (30.60%) and ethyl linoleate (21.56%) were the major components of seeds. The major ingredient of roots was palmitic acid (52.61%). The main ingredients of the stems were palmitic acid (38.38%) and ethyl linoleate (17.38%). All the different parts of essential oil were screened for cytotoxicity. The roots and stems showed the inhibitory effects against HepG-2 with IC50 levels of 613.88 and 341.12mg/L. The leaves and roots showed the inhibitory effects against HeLa with IC50 levels of 267.76 and 348.35mg/L. All the six parts have inhibitory effects against SGC-7901 cell lines. [GRAPHICS] .

引用

页码：1938 / 1940

页数：3

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