Androgen levels, insulin sensitivity, and early insulin response in women with polycystic ovary syndrome: a long-term follow-up study

被引：12
|
作者：
Hudecova, Miriam [1 ]
Holte, Jan [1 ]
Moby, Lena [1 ]
Olovsson, Matts [1 ]
Stridsberg, Mats [2 ]
Larsson, Anders [2 ]
Berglund, Lars [3 ]
Berne, Christian [2 ]
Poromaa, Inger Sundstrom [1 ]
机构：
[1] Uppsala Univ, Dept Womens & Childrens Hlth, S-75185 Uppsala, Sweden
[2] Uppsala Univ, Dept Med Sci, Uppsala, Sweden
[3] Uppsala Clin Res Ctr, Uppsala, Sweden
来源：
FERTILITY AND STERILITY | 2011年 / 95卷 / 03期
关键词：
Polycystic ovary syndrome; long-term follow-up; insulin sensitivity; intravenous glucose tolerance test; hyperinsulinemic; euglycemic clamp; testosterone; HORMONE-BINDING GLOBULIN; MENSTRUAL-CYCLE; RESISTANCE; SECRETION; GLUCOSE; HISTORY; INDEX; RISK;
D O I：
10.1016/j.fertnstert.2010.09.050
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Thirty-four women with polycystic ovary syndrome who previously had participated in studies with intravenous glucose tolerance test and hyperinsulinemic, euglycemic clamp between 1987 and 1995 underwent anthropometric, endocrine (T and sex-hormone binding globulin serum concentration), and metabolic (intravenous glucose tolerance test, hyperinsulinemic, euglycemic clamp, and androgens) measurements. Free androgen levels and beta-cell function decreased over time in women with polycystic ovary syndrome, but insulin sensitivity remained unaltered. (Fertil Steril (R) 2011;95:1146-8. (c) 2011 by American Society for Reproductive Medicine.)
引用
收藏
页码：1146 / 1148
页数：3
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