A Potential Role For Apparent Diffusion Coefficient in the Diagnosis of Trilateral Retinoblastoma

被引:6
作者
Sait, Sameer Farouk [1 ]
Haque, Sofia [2 ,5 ]
Karimi, Sasan [2 ,5 ]
Rebeiz, Karim J. [2 ]
Francis, Jasmine H. [3 ]
Marr, Brian P. [3 ]
Abramson, David H. [3 ,7 ]
Souweidane, Mark M. [4 ,8 ]
Dunkel, Ira J. [1 ,6 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Dept Pediat, H 1107,1275 York Ave, New York, NY 10065 USA
[2] Mem Sloan Kettering Canc Ctr, Dept Radiol, 1275 York Ave, New York, NY 10021 USA
[3] Mem Sloan Kettering Canc Ctr, Dept Surg, 1275 York Ave, New York, NY 10021 USA
[4] Mem Sloan Kettering Canc Ctr, Dept Neurosurg, 1275 York Ave, New York, NY 10021 USA
[5] Weill Cornell Med Coll, Dept Radiol, New York, NY USA
[6] Weill Cornell Med Coll, Dept Pediat, New York, NY USA
[7] Weill Cornell Med Coll, Dept Ophthalmol, New York, NY USA
[8] Weill Cornell Med Coll, Dept Neurosurg, New York, NY USA
关键词
retinoblastoma; diffusion-weighted imaging; pineoblastoma; diagnostic radiology; MRI-BASED ASSESSMENT; AGED; 0-5; YEARS; PINEAL-GLAND; LARGE POPULATION; PINEALOBLASTOMA; CHILDREN;
D O I
10.1097/MPH.0000000000001523
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
We attempted to investigate the potential role for apparent diffusion coefficient (ADC) to diagnose trilateral retinoblastoma (TRb) by retrospectively reviewing brain magnetic resonance images of retinoblastoma patients. Observations: The median ADC measured 620.95 for TRb (n=6) and 1238.5 for normal pineal gland in bilateral retinoblastoma (n=8). Monitoring ADC trends aided in establishing the appropriate diagnoses in 3 patients (2 TRb, 1 benign pineal cyst). Conclusions: Our results provide baseline reference data and describe the importance of downward trending ADC which should prompt consideration of TRb. Unchanged high/nonrestricted values (>1000) may distinguish those with benign pineal tissue and obviate invasive neurosurgical procedures.
引用
收藏
页码:238 / 243
页数:6
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