Signal recognition particles in chloroplasts, bacteria, yeast and mammals (Review)

被引：86
作者：
Pool, MR [1 ]
机构：
[1] Univ Manchester, Fac Life Sci, Manchester M13 9PT, Lancs, England
来源：
MOLECULAR MEMBRANE BIOLOGY | 2005年 / 22卷 / 1-2期
基金：
英国生物技术与生命科学研究理事会;
关键词：
signal recognition particle; targeting; ribosome; GTPase; structure/function;
D O I：
10.1080/09687860400026348
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The Signal Recognition Particle (SRP) plays a critical role in the sorting of nascent secretory and membrane proteins. Remarkably, this function has been conserved from bacteria, where SRP delivers proteins to the inner membrane, through to eukaryotes, where SRP is required for targeting of proteins to the endoplasmic reticulum. This review focuses on present understanding of SRP structure and function and the relationship between the two. Furthermore, the similarities and differences in the structure, function and cellular role of SRP in bacteria, chloroplasts, fungi and mammals will be stressed.
引用
收藏
页码：3 / 15
页数：13
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