Molding Cell Beads for Rapid Construction of Macroscopic 3D Tissue Architecture

被引：260
作者：
Matsunaga, Yukiko T. [1 ,2 ]
Morimoto, Yuya [1 ]
Takeuchi, Shoji [1 ,2 ]
机构：
[1] Univ Tokyo, Inst Ind Sci, Meguro Ku, Tokyo 1538505, Japan
[2] BEANS Project, Life BEANS Ctr, Meguro Ku, Tokyo 1538505, Japan
来源：
ADVANCED MATERIALS | 2011年 / 23卷 / 12期
关键词：
FABRICATION;
D O I：
10.1002/adma.201004375
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A microfluidic system was used to prepare a large number of size-controlled collagen gel beads to form microtissue units, "cell beads", as tissue building blocks. By stacking cell beads into a doll-shaped silicone chamber, millimeter-thick tissue with uniform cell density was formed rapidly. The bead structure allowed the application into the 3D printing, achieving automated geometrical control of the formed tissues for the fabrication of functional complex tissues. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：H90 / H94
页数：5
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