Putative Mechanisms of Viral Transmission and Molecular Dysregulation of Mammary Epithelial Cells by Human Papillomavirus: Implications for Breast Cancer

被引：1

作者：

de Lima, E. G. ^{[1
]}

do Amaral, C. M. M. ^{[1
]}

Peixe, F. C. Q. ^{[2
]}

Gurgel, A. P. A. D. ^{[1
]}

da Costa Silva Neto, J. ^{[2
]}

de Freitas, A. C. ^{[1
]}

机构：

[1] Univ Fed Pernambuco, Dept Genet, Lab Mol Studies & Expt Therapy LEMTE, Ave Prof Moraes Rego S-N, BR-50670901 Recife, PE, Brazil

[2] Univ Fed Pernambuco, Dept Histol & Embryol, Ave Prof Moraes Rego S-N, BR-50670901 Recife, PE, Brazil

来源：

CURRENT MOLECULAR MEDICINE | 2016年 / 16卷 / 07期

关键词：

Breast cancer; human papillomavirus (HPV); etiological factor; E6 and E7 oncoproteins; HER2; BRCA1; BRCA2; ESTROGEN-RECEPTOR-ALPHA; NO EVIDENCE; HPV DNA; VIRUS; ASSOCIATION; INFECTION; CARCINOMAS; SEQUENCES; BRCA1; PREVALENCE;

D O I：

10.2174/1566524016666160805120410

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Breast cancer is the most common cancer in women worldwide. Several studies have demonstrated the presence of Human papillomavirus (HPV) DNA in breast cancer samples. However, the role of HPV in breast carcinogenesis is not clear, and the interaction mechanisms between this infectious agent and the breast cancer cell need to be more fully clarified. In this article, we discuss the putative roles of HPV infection in breast carcinogenesis.

引用

页码：650 / 659

页数：10

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