Antimicrobial properties of chitosan and mode of action: A state of the art review

被引：2111

作者：

Kong, Ming ^{[1
,2
]}

Chen, Xi Guang ^{[2
]}

Xing, Ke ^{[3
]}

Park, Hyun Jin ^{[1
]}

机构：

[1] Korea Univ, Sch Life Sci & Biotechnol, Seoul 136701, South Korea

[2] Ocean Univ China, Coll Marine Life Sci, Qingdao 266003, Shandong, Peoples R China

[3] Xuzhou Normal Univ, Coll Life Sci, Xuzhou 221116, Jiangsu, Peoples R China

来源：

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY | 2010年 / 144卷 / 01期

关键词：

Chitosan; Antimicrobial activity; Mechanism; Application; DIFFERENT MOLECULAR-WEIGHTS; ESCHERICHIA-COLI O157-H7; GRAM-POSITIVE BACTERIA; ANTIBACTERIAL ACTIVITY; STAPHYLOCOCCUS-AUREUS; IN-VITRO; BIOLOGICAL-PROPERTIES; QUATERNIZED CHITOSAN; NEGATIVE BACTERIA; MAILLARD REACTION;

D O I：

10.1016/j.ijfoodmicro.2010.09.012

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Owing to its high biodegradability, and nontoxicity and antimicrobial properties, chitosan is widely-used as an antimicrobial agent either alone or blended with other natural polymers. To broaden chitosan's antimicrobial applicability, comprehensive knowledge of its activity is necessary. The paper reviews the current trend of investigation on antimicrobial activities of chitosan and its mode of action. Chitosan-mediated inhibition is affected by several factors can be classified into four types as intrinsic, environmental, microorganism and physical state, according to their respective roles. In this review, different physical states are comparatively discussed. Mode of antimicrobial action is discussed in parts of the active compound (chitosan) and the target (microorganisms) collectively and independently in same complex. Finally, the general antimicrobial applications of chitosan and perspectives about future studies in this field are considered. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：51 / 63

页数：13

共 115 条

[1] Synthesis of iron-crosslinked chitosan succinate and iron-crosslinked hydroxamated chitosan succinate and their in vitro evaluation as potential matrix materials for oral theophylline sustained-release beads [J].

Aiedeh, K ;

Taha, MO .

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2001, 13 (02) :159-168

[2] FUNGICIDAL EFFECT OF CHITOSAN ON FUNGI OF VARYING CELL-WALL COMPOSITION [J].

ALLAN, CR ;

HADWIGER, LA .

EXPERIMENTAL MYCOLOGY, 1979, 3 (03) :285-287

[3]

[Anonymous], 2008, FRONT MAT SCI CHINA, DOI DOI 10.1007/S11706-008-0036-2

[4]

[Anonymous], 2005, J FOOD SCI

[5]

[Anonymous], 1995, Food additives code, P449

[6]

Arvanitoyannis IS, 1999, J MACROMOL SCI R M C, VC39, P205

[7] Chitosan and gelatin based edible films: state diagrams, mechanical and permeation properties [J].

Arvanitoyannis, IS ;

Nakayama, A ;

Aiba, S .

CARBOHYDRATE POLYMERS, 1998, 37 (04) :371-382

[8] THE ELECTROPHORETIC MOBILITY OF GRAM-NEGATIVE AND GRAM-POSITIVE BACTERIA - AN ELECTROKINETIC ANALYSIS [J].

BAYER, ME ;

SLOYER, JL .

JOURNAL OF GENERAL MICROBIOLOGY, 1990, 136 :867-874

[9] Interactions between dendrimer biocides and bacterial membranes [J].

Chen, CZS ;

Cooper, SL .

BIOMATERIALS, 2002, 23 (16) :3359-3368

[10] Immobilization of chitosan gel with cross-linking reagent on PNIPAAm gel/PP nonwoven composites surface [J].

Chen, KS ;

Ku, YA ;

Lee, CH ;

Lin, HR ;

Lin, FH ;

Chen, TM .

MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS, 2005, 25 (04) :472-478

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