Synthesis and pharmacological evaluation of some naphtho [2,1-b]FURO[3,2-d] pyrimidines

被引：0
|
作者：
Mathias, P [1 ]
Vaidya, VP [1 ]
机构：
[1] Kuvempu Univ, Dept Chem, Shankaraghatta 577451, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2005年 / 14卷 / 03期
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D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Synthesis of 2-chloromethyl-4-chloronaphtho [2,1-b] furo [3,2-d] pyrimidine 5 is reported. The conversion of 5 into various substituted derivatives by reacting it with different amines, thiourea, active methylene compounds and alkoxides has been described. The newly synthesized compounds have been characterized by elemental analysis and spectral data. The selected compounds have been screened for antibacterial, antifungal and anthelmintic activities.
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页码：189 / 192
页数：4
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