Methamphetamine-induced Fos expression in the substantia nigra pars reticulata in rats with a unilateral 6-OHDA lesion of the nigrostriatal fibers

被引：5

作者：

Ishida, Y

Todaka, K

Kuwahara, I

Nakane, H

Ishizuka, Y

Nishimori, T

Mitsuyama, Y

机构：

[1] Miyazaki Med Coll, Dept Psychiat, Miyazaki 8891692, Japan

[2] Miyazaki Med Coll, Div Biol, Miyazaki 8891692, Japan

来源：

NEUROSCIENCE RESEARCH | 1998年 / 30卷 / 04期

关键词：

6-hydroxydopamine; methamphetamine; Fos; striatum; substantia nigra pars reticulata; rat;

D O I：

10.1016/S0168-0102(98)00015-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In rats with a unilateral 6-hydroxydopamine (6-OHDA)-induced lesion in the nigrostriatal fibers, methamphetamine (3 mg/kg, i.p.) induced Fos-like immunoreactivity (FLI), which was inhibited by pretreatment with N-methyl-D-aspartate antagonist MK-801 (1 mg/kg, i.p.), not only in the medial striatum contraiateral to the lesion but also in the substantia nigra pars reticulata (SNr) ipsilateral to the lesion. Thus, hemispheric asymmetries in FLI were induced by methamphetamine in the medial striatum and the SNr in the 6-OHDA model of turning which may be related to the altered function of glutamatergic transmission. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：355 / 360

页数：6

共 50 条

[21] BIOTRANSFORMATION OF L-DOPA IN STRIATUM AND SUBSTANTIA-NIGRA OF RATS WITH A UNILATERAL, NIGROSTRIATAL LESION - A MICRODIALYSIS STUDY
SARRE, S
HERREGODTS, P
DELEU, D
DEVRIEZE, A
DEKLIPPEL, N
EBINGER, G
MICHOTTE, Y
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1992, 346 (03) : 277 - 285
[22] Chronic methamphetamine-induced neurodegeneration: Differential vulnerability of ventral tegmental area and substantia nigra pars compacta dopamine neurons
Du, Yijuan
Lee, You Bin
Graves, Steven M.
NEUROPHARMACOLOGY, 2021, 200
[23] Effect of 6-OHDA injection on the AMPA glutamate receptor subunits in the substantia nigra of Sprague-Dawley rats
He, Y
Lee, T
Leong, SK
NEUROSCIENCE LETTERS, 1998, 241 (01) : 1 - 4
[24] Subchronic administration of L-DOPA to adult rats with a unilateral 6-hydroxydopamine lesion of dopamine neurons results in a sensitization of enhanced GABA release in the substantia nigra, pars reticulata
Yamamoto, Noriko
Pierce, R. Christopher
Soghomonian, Jean-Jacques
BRAIN RESEARCH, 2006, 1123 : 196 - 200
[25] Failure of estrogen to protect the substantia nigra pars compacta of female rats from lesion induced by 6-hydroxydopamine
Ferraz, AC
Xavier, LL
Hernandes, S
Sulzbach, M
Viola, GG
Anselmo-Franci, JA
Achaval, M
Da Cunha, C
BRAIN RESEARCH, 2003, 986 (1-2) : 200 - 205
[26] Apomorphine-induced alterations in striatal and substantia nigra pars reticulata glutamate following unilateral loss of striatal dopamine
Touchon, JC
Holmer, HK
Moore, C
McKee, BL
Frederickson, J
Meshul, CK
EXPERIMENTAL NEUROLOGY, 2005, 193 (01) : 131 - 140
[27] Cyclic AMP responsive element binding protein phosphorylation and persistent expression of levodopa-induced response alterations in unilateral nigrostriatal 6-OHDA lesioned rats
Oh, JD
Chartisathian, K
Ahmed, SM
Chase, TN
JOURNAL OF NEUROSCIENCE RESEARCH, 2003, 72 (06) : 768 - 780
[28] Immunohistochemical detection Of L-DOPA-derived dopamine within serotonergic fibers in the striatum and the substantia nigra pars reticulata in Parkinsonian model rats
Yamada, Hiromasa
Aimi, Yoshinari
Nagatsu, Ikuko
Taki, Kousuke
Kudo, Motoi
Arai, Ryohachi
NEUROSCIENCE RESEARCH, 2007, 59 (01) : 1 - 7
[29] Lesion of the pedunculopontine nucleus reverses hyperactivity of the subthalamic nucleus and substantia nigra pars reticulata in a 6-hydroxydopamine rat model
Breit, S.
Lessmann, L.
Unterbrink, D.
Popa, R. C.
Gasser, T.
Schulz, J. B.
EUROPEAN JOURNAL OF NEUROSCIENCE, 2006, 24 (08) : 2275 - 2282
[30] Characterisation of spatial neglect induced by unilateral 6-OHDA lesions on a choice reaction time task in rats
Heuer, Andreas
Dunnett, Stephen B.
BEHAVIOURAL BRAIN RESEARCH, 2013, 237 : 215 - 222

← 1 2 3 4 5 →