Gene therapy for pancreatic cancer

被引：0

作者：

Takeda, S ^{[1
]}

Nakao, A ^{[1
]}

Miyoshi, K ^{[1
]}

Takagi, H ^{[1
]}

机构：

[1] Nagoya Univ, Sch Med, Dept Surg 2, Showa Ku, Nagoya, Aichi 466, Japan

来源：

SEMINARS IN SURGICAL ONCOLOGY | 1998年 / 15卷 / 01期

基金：

美国国家卫生研究院;

关键词：

pancreatic neoplasms surgery genetics pathology therapy; gene therapy; immunotherapy; genetic vectors; RNA antisense; prodrugs; gene expression; genetic transduction; ras genes; viral genes; p53; genes; retroviridae; simplexvirus; vaccinia virus; tumor suppressor genes; ganciclovir; thymidine kinase; MDR genes; point mutation; interleukins; interferons; oncogenes; tumor necrosis factor; carcinoembryonic antigen;

D O I：

10.1002/(SICI)1098-2388(199807/08)15:1<57::AID-SSU10>3.0.CO;2-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

It has been approximately 7 years since the introduction of gene therapy. Since conventional procedures such as surgery, chemotherapy, and radiotherapy have had limited therapeutic value for cancer patients, the evolution of gene therapy seems a promising alternative to many researchers and clinicians. Indeed, about half of all gene therapy treatments are administered to patients with cancer. However, there are relatively few studies of using gene therapy with pancreatic cancer. We will review the general concept of gene therapy for cancer and its accomplishments to date. (C) 1998 Wiley-Liss, Inc.

引用

页码：57 / 61

页数：5

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