The Scandinavian Solutions for Wellness study - a two-arm observational study on the effectiveness of lifestyle intervention on subjective well-being and weight among persons with psychiatric disorders

被引:25
作者
Porsdal, Vibeke [1 ]
Beal, Catherine [2 ]
Kleivenes, Ole Kristian [3 ]
Martinsen, Egil W. [4 ]
Lindstrom, Eva [5 ]
Nilsson, Harriet [6 ]
Svanborg, Par [7 ]
机构
[1] Eli Lilly Danmark AS, DK-2800 Lyngby, Denmark
[2] Keyrus BioPharma, F-92300 Levallois Perret, France
[3] Eli Lilly Norge AS, N-0601 Oslo, Norway
[4] Aker Univ Hosp, Clin Psychiat Hlth, Oslo, Norway
[5] Malmo Univ Hosp, Clin Forens Psychiat, Malmo, Sweden
[6] ICON Clin Res Ltd, SE-16927 Solna, Sweden
[7] Karolinska Inst, Dept Clin Neurosci, Eli Lilly Sweden AB, Stockholm, Sweden
关键词
SERIOUS MENTAL-ILLNESS; QUALITY-OF-LIFE; BEHAVIORAL-THERAPY; OBESE-PATIENTS; SCHIZOAFFECTIVE DISORDER; MANAGEMENT PROGRAM; GAIN; SCHIZOPHRENIA; OLANZAPINE; ASSOCIATION;
D O I
10.1186/1471-244X-10-42
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Background: Solutions for Wellness (SfW) is an educational 3-month program concerning nutrition and exercise for persons with psychiatric disorders on psychotropic medication, who have weight problems. This observational study assessed the impact of SfW on subjective well-being, weight and waist circumference (WC). Methods: Data was collected at 49 psychiatric clinics. Where the SfW program was offered patients could enter the intervention group; where not, the control group. Subjective well-being was measured by the Subjective Well-being under Neuroleptics scale (SWN), at baseline, at the end of SfW participation, and at a follow-up 6 months after baseline. Demographic, disease and treatment data was also collected. Results: 314 patients enrolled in the SfW group, 59 in the control group. 54% of the patients had schizophrenia, 67% received atypical antipsychotics, 56% were female. They averaged 41 +/- 12.06 years and had a BMI of 31.4 +/- 6.35. There were significant differences at baseline between groups for weight, SWN total score and other factors. Stepwise logistic models controlling for baseline covariates yielded an adjusted non-significant association between SfW program participation and response in subjective well-being (SWN increase). However, statistically significant associations were found between program participation and weight-response (weight loss or gain < 1 kg) OR = 2; 95% CI [1.1; 3.7] and between program participation and WC-response (WC decrease or increase < 2 cm) OR = 5; 95% CI [2.4; 10.3]), at 3 months after baseline. Conclusions: SfW program participation was associated with maintaining or decreasing weight and WC but not with improved subjective well-being as measured with the SWN scale.
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页数:12
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