The Scandinavian Solutions for Wellness study - a two-arm observational study on the effectiveness of lifestyle intervention on subjective well-being and weight among persons with psychiatric disorders

被引:25
作者
Porsdal, Vibeke [1 ]
Beal, Catherine [2 ]
Kleivenes, Ole Kristian [3 ]
Martinsen, Egil W. [4 ]
Lindstrom, Eva [5 ]
Nilsson, Harriet [6 ]
Svanborg, Par [7 ]
机构
[1] Eli Lilly Danmark AS, DK-2800 Lyngby, Denmark
[2] Keyrus BioPharma, F-92300 Levallois Perret, France
[3] Eli Lilly Norge AS, N-0601 Oslo, Norway
[4] Aker Univ Hosp, Clin Psychiat Hlth, Oslo, Norway
[5] Malmo Univ Hosp, Clin Forens Psychiat, Malmo, Sweden
[6] ICON Clin Res Ltd, SE-16927 Solna, Sweden
[7] Karolinska Inst, Dept Clin Neurosci, Eli Lilly Sweden AB, Stockholm, Sweden
关键词
SERIOUS MENTAL-ILLNESS; QUALITY-OF-LIFE; BEHAVIORAL-THERAPY; OBESE-PATIENTS; SCHIZOAFFECTIVE DISORDER; MANAGEMENT PROGRAM; GAIN; SCHIZOPHRENIA; OLANZAPINE; ASSOCIATION;
D O I
10.1186/1471-244X-10-42
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Background: Solutions for Wellness (SfW) is an educational 3-month program concerning nutrition and exercise for persons with psychiatric disorders on psychotropic medication, who have weight problems. This observational study assessed the impact of SfW on subjective well-being, weight and waist circumference (WC). Methods: Data was collected at 49 psychiatric clinics. Where the SfW program was offered patients could enter the intervention group; where not, the control group. Subjective well-being was measured by the Subjective Well-being under Neuroleptics scale (SWN), at baseline, at the end of SfW participation, and at a follow-up 6 months after baseline. Demographic, disease and treatment data was also collected. Results: 314 patients enrolled in the SfW group, 59 in the control group. 54% of the patients had schizophrenia, 67% received atypical antipsychotics, 56% were female. They averaged 41 +/- 12.06 years and had a BMI of 31.4 +/- 6.35. There were significant differences at baseline between groups for weight, SWN total score and other factors. Stepwise logistic models controlling for baseline covariates yielded an adjusted non-significant association between SfW program participation and response in subjective well-being (SWN increase). However, statistically significant associations were found between program participation and weight-response (weight loss or gain < 1 kg) OR = 2; 95% CI [1.1; 3.7] and between program participation and WC-response (WC decrease or increase < 2 cm) OR = 5; 95% CI [2.4; 10.3]), at 3 months after baseline. Conclusions: SfW program participation was associated with maintaining or decreasing weight and WC but not with improved subjective well-being as measured with the SWN scale.
引用
收藏
页数:12
相关论文
共 35 条
[1]   Non-pharmacological management of anti psychotic-induced weight gain: systematic review and meta-analysis of randomised controlled trials [J].
Alvarez-Jimenez, Mario ;
Hetrick, Sarah E. ;
Gonzalez-Blanch, Cesar ;
Gleeson, John F. ;
McGorry, Patrick D. .
BRITISH JOURNAL OF PSYCHIATRY, 2008, 193 (02) :101-107
[2]   Attenuation of antipsychotic-induced weight gain with early behavioral intervention in drug-naive first-episode psychosis patients:: A randomized controlled trial [J].
Alvarez-Jimenez, Mario ;
Gonzalez-Blanch, Cesar ;
Vazquez-Barquero, Jose Luis ;
Perez-Iglesias, Rocio ;
Martinez-Garcia, Obdulia ;
Perez-Pardal, Teresa ;
Ramirez-Bonilla, Mari Luz ;
Crespo-Facorro, Benedicto .
JOURNAL OF CLINICAL PSYCHIATRY, 2006, 67 (08) :1253-1260
[3]  
[Anonymous], PREDICTION NEUROLEPT, DOI DOI 10.1007/978-3-7091-6636-9_10
[4]   Effects of behavioral therapy on weight loss in overweight and obese patients with schizophrenia or schizoaffective disorder [J].
Brar, JS ;
Ganguli, R ;
Pandina, G ;
Turkoz, I ;
Berry, S ;
Mahmoud, R .
JOURNAL OF CLINICAL PSYCHIATRY, 2005, 66 (02) :205-212
[5]   Weight management in a cohort of Irish inpatients with serious mental illness (SMI) using a modular behavioural programme. A preliminary service evaluation [J].
Bushe, Chris J. ;
McNamara, Dermot ;
Haley, Cliff ;
McCrossan, Mary Fleming ;
Devitt, Pat .
BMC PSYCHIATRY, 2008, 8 (1)
[6]   Effects of a 10-week weight control program on obese patients with schizophrenia or schizoaffective disorder: A 12-month follow up [J].
Chen, Chih-Ken ;
Chen, Yi-Chih ;
Huang, Yu-Shu .
PSYCHIATRY AND CLINICAL NEUROSCIENCES, 2009, 63 (01) :17-22
[7]   Cardiometabolic Risk of Second-Generation Antipsychotic Medications During First-Time Use in Children and Adolescents [J].
Correll, Christoph U. ;
Manu, Peter ;
Olshanskiy, Vladimir ;
Napolitano, Barbara ;
Kane, John M. ;
Malhotra, Anil K. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2009, 302 (16) :1765-1773
[8]   Psychometric properties of the Subjective Well-Being Under Neuroleptics Scale and the Subjective Deficit Syndrome Scale [J].
de Haan, L ;
Weisfelt, M ;
Dingemans, PMAJ ;
Linszen, DH ;
Wouters, L .
PSYCHOPHARMACOLOGY, 2002, 162 (01) :24-28
[9]  
Evans S, 2005, AUST NZ J PSYCHIAT, V39, P479, DOI 10.1111/j.1440-1614.2005.01607.x
[10]   Interventions to reduce weight gain in schizophrenia [J].
Faulkner, G. ;
Cohn, T. ;
Remington, G. .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2007, (01)