Demographic characteristics, treatment, and outcome of patients with Kaposi sarcoma: Ten-year follow-up results of a single center

被引:1
作者
Gunes, Begum [1 ]
Mert, Omer [1 ]
Onsun, Nahide [1 ]
机构
[1] Bezmialem Vakif Univ, Fac Med, Dept Dermatol & Venereol, Istanbul, Turkey
关键词
HHV-8; Interferon; Kaposi sarcoma; AIDS;
D O I
10.1111/jocd.14426
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background Clinical features, types of Kaposi sarcoma, and treatment outcomes have not been well-defined in Turkey. In this study, we reviewed records of the patients who had been diagnosed with Kaposi sarcoma in the last decade in a single center and evaluated treatment results. Methods Medical records of the Kaposi sarcoma patients seen in the last decade in a single tertiary center were evaluated in detail. Results A total of 27 patients were identified; 18 patients had been checked for HHV8; and 16 of those patients were positive for HHV8. One patient was positive for HIV. Two patients having mycosis fungoides and myasthenia graves developed iatrogenic KS after immunosuppressive treatments. Interferon alpha was used in 21 patients; 8 patients achieved complete response; and 11 patients achieved a partial response. No serious side effects were observed. Systemic involvement did not develop in any patients except lymph node involvement in a patient with widespread skin lesions.
引用
收藏
页码:2559 / 2565
页数:7
相关论文
共 18 条
[1]   Distinct expression of Kaposi's sarcoma-associated herpesvirus-encoded proteins in Kaposi's sarcoma and multicentric Castleman's disease [J].
Abe, Yasuhisa ;
Matsubara, Daisuke ;
Gatanaga, Hiroyuki ;
Oka, Shinichi ;
Kimura, Satoshi ;
Sasao, Yuki ;
Saitoh, Kiyoshi ;
Fujii, Takeshi ;
Sato, Yuko ;
Sata, Tetsutaro ;
Katano, Harutaka .
PATHOLOGY INTERNATIONAL, 2006, 56 (10) :617-624
[2]   The Spectrum of Underlying Causes of latrogenic Kaposi's Sarcoma in a Large Series: A Retrospective Study [J].
Baykal, Can ;
Atci, Tugba ;
Buyukbabani, Nesimi ;
Kutlay, Armagan .
INDIAN JOURNAL OF DERMATOLOGY, 2019, 64 (05) :392-399
[3]   KAPOSIS SARCOMA AMONG PERSONS WITH AIDS - A SEXUALLY-TRANSMITTED INFECTION [J].
BERAL, V ;
PETERMAN, TA ;
BERKELMAN, RL ;
JAFFE, HW .
LANCET, 1990, 335 (8682) :123-128
[4]   IDENTIFICATION OF HERPESVIRUS-LIKE DNA-SEQUENCES IN AIDS-ASSOCIATED KAPOSIS-SARCOMA [J].
CHANG, Y ;
CESARMAN, E ;
PESSIN, MS ;
LEE, F ;
CULPEPPER, J ;
KNOWLES, DM ;
MOORE, PS .
SCIENCE, 1994, 266 (5192) :1865-1869
[5]  
Deichmann M, 1998, BRIT J DERMATOL, V139, P1052
[6]   Kaposi sarcoma-associated herpesvirus infects monotypic (IgMλ) but polyclonal naive B cells in Castleman disease and associated lymphoproliferative disorders [J].
Du, MQ ;
Liu, HX ;
Diss, TC ;
Ye, HT ;
Hamoudi, RA ;
Dupin, N ;
Meignin, V ;
Oksenhendler, E ;
Boshoff, C ;
Isaacson, PG .
BLOOD, 2001, 97 (07) :2130-2136
[7]   CHANGES IN KAPOSIS-SARCOMA INDUCED BY DAPSONE [J].
FANTI, PA ;
TOSTI, A ;
PILERI, S .
CLINICAL AND EXPERIMENTAL DERMATOLOGY, 1991, 16 (06) :441-443
[8]   CLINICAL MANIFESTATIONS OF CLASSICAL, ENDEMIC AFRICAN, AND EPIDEMIC AIDS-ASSOCIATED KAPOSIS-SARCOMA [J].
FRIEDMANKIEN, AE ;
SALTZMAN, BR .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1990, 22 (06) :1237-1250
[9]   A PRELIMINARY COMMUNICATION ON EXTENSIVELY DISSEMINATED KAPOSIS SARCOMA IN YOUNG HOMOSEXUAL MEN [J].
GOTTLIEB, GJ ;
RAGAZ, A ;
VOGEL, JV ;
FRIEDMANKIEN, A ;
RYWLIN, AM ;
WEINER, EA ;
ACKERMAN, AB .
AMERICAN JOURNAL OF DERMATOPATHOLOGY, 1981, 3 (02) :111-114
[10]   Clinical features of Kaposi's sarcoma: experience from a Taiwanese medical center [J].
Huang, Alice Ya-Yun ;
Lin, Chi-Ling ;
Chen, Gwo-Shing ;
Hu, Stephen Chu-Sung .
INTERNATIONAL JOURNAL OF DERMATOLOGY, 2019, 58 (12) :1388-1397