Comparison of Lyme Disease in the United States and Europe

被引：149

作者：

Marques, Adriana R. ^{[1
]}

Strle, Franc ^{[2
]}

Wormser, Gary P. ^{[3
]}

机构：

[1] NIH, Bldg 10, Bethesda, MD 20892 USA

[2] Univ Med Ctr Ljubljana, Ljubljana, Slovenia

[3] New York Med Coll, Valhalla, NY 10595 USA

来源：

EMERGING INFECTIOUS DISEASES | 2021年 / 27卷 / 08期

基金：

美国国家卫生研究院;

关键词：

ERYTHEMA MIGRANS; BORRELIA-BURGDORFERI; PERIPHERAL NEUROPATHY; TICK BITE; CHILDREN; DIAGNOSIS; NEUROBORRELIOSIS; MANIFESTATIONS; ARTHRITIS; DURATION;

D O I：

10.3201/eid2708.204763

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Lyme disease, or Lyme borreliosis, is the most common tickborne disease in the United States and Europe. In both locations, Ixodes species ticks transmit the Borrelia burgdorferi sensu lato bacteria species responsible for causing the infection. The diversity of Borrelia species that cause human infection is greater in Europe; the 2 B. burgdorferi s.l. species collectively responsible for most infections in Europe, B. afzelii and B. garinii, are not found in the United States, where most infections are caused by B. burgdorferi sensu stricto. Strain differences seem to explain some of the variation in the clinical manifestations of Lyme disease, which are both minor and substantive, between the United States and Europe. Future studies should attempt to delineate the specific virulence factors of the different species of B. burgdorferi s.l. responsible for these variations in clinical features.

引用

页码：2017 / 2024

页数：8

共 49 条

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