Approach to hypoglycemia in infants and children

被引:30
作者
Gandhi, Kajal [1 ]
机构
[1] Nationwide Childrens Hosp, Endocrinol Sect, 700 Childrens Dr, Columbus, OH 43205 USA
关键词
Endocrinology; hypoglycemia; children; PERSISTENT HYPERINSULINEMIC HYPOGLYCEMIA; CONGENITAL HYPERINSULINISM; NEONATAL HYPOGLYCEMIA; NEURODEVELOPMENTAL OUTCOMES; DEXTROSE GEL; GLUCOSE; MANAGEMENT; MUTATIONS; DIAGNOSIS; DEFICIENCY;
D O I
10.21037/tp.2017.10.05
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Hypoglycemia is a heterogeneous disorder with many different possible etiologies, including hyperinsulinism, glycogen storage disorders, fatty acid disorders, hormonal deficiencies, and metabolic defects, among others. This condition affects newborns to adolescents, with various approaches to diagnosis and management. This paper will review current literature on the history of hypoglycemia, current discussion on the definition of hypoglycemia, as well as etiologies, diagnosis, and management.
引用
收藏
页码:408 / 420
页数:13
相关论文
共 91 条
[1]   Clinical Report-Postnatal Glucose Homeostasis in Late-Preterm and Term Infants [J].
Adamkin, David H. .
PEDIATRICS, 2011, 127 (03) :575-579
[2]   Costello Syndrome and hyperinsulinemic hypoglycemia [J].
Alexander, S ;
Ramadan, D ;
Alkhayyat, H ;
Al-Sharkawi, I ;
Backer, KCA ;
El-Sabban, F ;
Hussain, K .
AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 2005, 139A (03) :227-230
[3]  
Alexandrescu S, 2010, INT J CLIN EXP PATHO, V3, P691
[4]  
Alkhayyat H, 2006, J PEDIATR ENDOCR MET, V19, P1451
[5]   Congenital hyperinsulinism: current trends in diagnosis and therapy [J].
Arnoux, Jean-Baptiste ;
Verkarre, Virginie ;
Saint-Martin, Cecile ;
Montravers, Francoise ;
Brassier, Anais ;
Valayannopoulos, Vassili ;
Brunelle, Francis ;
Fournet, Jean-Christophe ;
Robert, Jean-Jacques ;
Aigrain, Yves ;
Bellanne-Chantelot, Christine ;
de Lonlay, Pascale .
ORPHANET JOURNAL OF RARE DISEASES, 2011, 6
[6]   Clinical and histological heterogeneity of congenital hyperinsulinism due to paternally inherited heterozygous ABCC8/KCNJ11 mutations [J].
Arya, Ved Bhushan ;
Guemes, Maria ;
Nessa, Azizun ;
Alam, Syeda ;
Shah, Pratik ;
Gilbert, Clare ;
Senniappan, Senthil ;
Flanagan, Sarah E. ;
Ellard, Sian ;
Hussain, Khalid .
EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2014, 171 (06) :685-695
[7]   HEPATIC GLYCOGEN-SYNTHETASE DEFICIENCY - DEFINITION OF SYNDROME FROM METABOLIC AND ENZYME STUDIES ON A 9-YEAR-OLD GIRL [J].
AYNSLEYGREEN, A ;
WILLIAMSON, DH ;
GITZELMANN, R .
ARCHIVES OF DISEASE IN CHILDHOOD, 1977, 52 (07) :573-579
[8]   Glycogen synthase deficiency (glycogen storage disease type 0) presenting with hyperglycemia and glucosuria: Report of three new mutations [J].
Bachrach, BE ;
Weinstein, DA ;
Orho-Melander, M ;
Burgess, A ;
Wolfsdorf, JI .
JOURNAL OF PEDIATRICS, 2002, 140 (06) :781-783
[9]  
Baker P II, 1993, GENEREVIEWS
[10]   Disturbed lipid metabolism in glycogen storage disease type 1 [J].
Bandsma, RHJ ;
Smit, GPA ;
Kuipers, F .
EUROPEAN JOURNAL OF PEDIATRICS, 2002, 161 (Suppl 1) :S65-S69