Sepsis 2018: Definitions and Guideline Changes

被引：254

作者：

Napolitano, Lena M. ^{[1
]}

机构：

[1] Univ Michigan Hlth Syst, Acute Care Surg Trauma & Surg Crit Care, Ann Arbor, MI USA

来源：

SURGICAL INFECTIONS | 2018年 / 19卷 / 02期

关键词：

sepsis; sepsis guidelines; Sepsis-3; definition; septic shock; Surviving Sepsis Campaign; INTERNATIONAL CONSENSUS DEFINITIONS; INFLAMMATORY RESPONSE SYNDROME; ORGAN FAILURE ASSESSMENT; IN-HOSPITAL MORTALITY; GOAL-DIRECTED THERAPY; SEPTIC SHOCK; INTENSIVE-CARE; HEMOGLOBIN THRESHOLD; PROGNOSTIC ACCURACY; CLINICAL-CRITERIA;

D O I：

10.1089/sur.2017.278

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Background: Sepsis is a global healthcare issue and continues to be the leading cause of death from infection. Early recognition and diagnosis of sepsis is required to prevent the transition into septic shock, which is associated with a mortality rate of 40% or more. Discussion: New definitions for sepsis and septic shock (Third International Consensus Definitions for Sepsis and Septic Shock [Sepsis-3]) have been developed. A new screening tool for sepsis (quick Sequential Organ Failure Assessment [qSOFA]) has been proposed to predict the likelihood of poor outcome in out-of-intensive care unit (ICU) patients with clinical suspicion of sepsis. The Surviving Sepsis Campaign Guidelines were recently updated and include greater evidence-based recommendations for treatment of sepsis in attempts to reduce sepsis-associated mortality. This review discusses the new Sepsis-3 definitions and guidelines.

引用

页码：117 / 125

页数：9

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