Bilateral video-assisted thoracoscopic thymectomy has a surgical extent similar to that of transsternal extended thymectomy with more favorable early surgical outcomes for myasthenia gravis patients

被引:50
作者
Lee, Chang Young [1 ]
Kim, Dae Joon [1 ]
Lee, Jin Gu [1 ]
Park, In Kyu [1 ]
Bae, Mi Kyung [1 ]
Chung, Kyung Young [1 ]
机构
[1] Yonsei Univ, Coll Med, Dept Thorac & Cardiovasc Surg, Seoul, South Korea
来源
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES | 2011年 / 25卷 / 03期
关键词
Myasthenia gravis; Thoracoscopy; Thymectomy; AUTOIMMUNE MYASTHENIA; FOLLOW-UP; REMISSION; THYMOMA; VATET;
D O I
10.1007/s00464-010-1280-y
中图分类号
R61 [外科手术学];
学科分类号
摘要
This study aimed to introduce the authors' surgical technique of bilateral video-assisted thoracoscopic thymectomy (BVT) and to compare their early surgical results between BVT and transsternal extended thymectomy (T3-b thymectomy) for patients with myasthenia gravis (MG). The records of 114 patients who underwent either BVT (n = 55) or T3-b thymectomy (n = 59) for MG were reviewed retrospectively between January 2006 and November 2009. No surgical mortality or major morbidity occurred in either group. There was no conversion to open thymectomy, and no statistical difference was found in operation time between the two groups (112.2 +/- A 26.2 min for BVT vs. 130.7 +/- A 27.3 min for T-3b; p = 0.908). The duration of the chest tube, the length of the intensive care unit (ICU) or hospital stay, and the duration of opioid use for pain control were shorter in BVT group. The estimated blood loss and the total amount of drainage were greater in the T3-b thymectomy group. The specimen weights retrieved by BVT (72.5 +/- A 61.6 g) were similar to those retrieved by T3-b thymectomy (74.1 +/- A 38.2 g, p = 0.63) in nonthymomatous MG. The BVT was a safe procedure with a surgical extent and amount similar to those of T-3b thymectomy and less invasive for patients with MG. Long-term follow-up assessment and more extensive data are mandatory to verify the early surgical outcomes.
引用
收藏
页码:849 / 854
页数:6
相关论文
共 21 条
[1]   Bilateral video-assisted thoracoscopic thymectomy vs. extended transsternal thymectomy in myasthenia gravis: A prospective study [J].
Chang, PC ;
Chou, SH ;
Kao, EL ;
Cheng, YJ ;
Chuang, HY ;
Liu, CK ;
Lai, CL ;
Huang, MF .
EUROPEAN SURGICAL RESEARCH, 2005, 37 (04) :199-203
[2]  
Cooper J, 1998, CHEST SURG CLIN N AM, V8, P827
[3]   INVASIVE THYMOMA - THE ROLE OF MEDIASTINAL IRRADIATION FOLLOWING COMPLETE OR INCOMPLETE SURGICAL RESECTION [J].
CURRAN, WJ ;
KORNSTEIN, MJ ;
BROOKS, JJ ;
TURRISI, AT .
JOURNAL OF CLINICAL ONCOLOGY, 1988, 6 (11) :1722-1727
[4]  
Gripp S, 1998, CANCER-AM CANCER SOC, V83, P1495, DOI 10.1002/(SICI)1097-0142(19981015)83:8<1495::AID-CNCR4>3.3.CO
[5]  
2-F
[6]   Myasthenia gravis - Recommendations for clinical research standards [J].
Jaretzki, A ;
Barohn, RJ ;
Ernstoff, RM ;
Kaminski, HJ ;
Keesey, JC ;
Penn, AS ;
Sanders, DB .
NEUROLOGY, 2000, 55 (01) :16-23
[7]   Thymectomy for myasthenia gravis: Analysis of controversies - Patient management [J].
Jaretzki, A .
NEUROLOGIST, 2003, 9 (02) :77-92
[8]   Results of video-assisted thymectomy in patients with myasthenia gravis [J].
Mack, MJ ;
Landreneau, RJ ;
Yim, AP ;
Hazelrigg, SR ;
Scruggs, GR .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1996, 112 (05) :1352-1359
[9]   A MULTICENTER FOLLOW-UP-STUDY OF 1152 PATIENTS WITH MYASTHENIA-GRAVIS IN ITALY [J].
MANTEGAZZA, R ;
BEGHI, E ;
PAREYSON, D ;
ANTOZZI, C ;
PELUCHETTI, D ;
SGHIRLANZONI, A ;
COSI, V ;
LOMBARDI, M ;
PICCOLO, G ;
TONALI, P ;
EVOLI, A ;
RICCI, E ;
BATOCCHI, AP ;
ANGELINI, C ;
MICAGLIO, GF ;
MARCONI, G ;
TAIUTI, R ;
BERGAMINI, L ;
DURELLI, L ;
CORNELIO, F .
JOURNAL OF NEUROLOGY, 1990, 237 (06) :339-344
[10]   Video-assisted thoracoscopic extended thymectomy and extended transsternal thymectomy (T-3b) in non-thymomatous myasthenia gravis patients:: remission after 6 years of follow-up [J].
Mantegazza, R ;
Baggi, F ;
Bernasconi, P ;
Antozzi, C ;
Confalonieri, P ;
Novellino, L ;
Spinelli, L ;
Ferrò, MT ;
Beghi, E ;
Cornelio, F .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2003, 212 (1-2) :31-36