Photoreactivity of the Occipital Cortex Measured by Functional Magnetic Resonance Imaging-Blood Oxygenation Level Dependent in Migraine Patients and Healthy Volunteers: Pathophysiological Implications

被引：73

作者：

Martin, Helena ^{[1
]}

Sanchez del Rio, Margarita ^{[2
,3
]}

Lopez de Silanes, Carlos ^{[4
]}

Alvarez-Linera, Juan ^{[2
,3
]}

Antonio Hernandez, Juan ^{[5
]}

Pareja, Juan A. ^{[4
,6
,7
]}

机构：

[1] Univ Hosp Fdn Alcorcon, Dept Internal Med, Madrid 28922, Spain

[2] Hosp Ruber Int, Dept Neurol, Madrid, Spain

[3] Hosp Ruber Int, Dept Radiol, Madrid, Spain

[4] Univ Hosp Fdn Alcorcon, Dept Neurol, Madrid 28922, Spain

[5] Rey Juan Carlos Univ, Fac Phys, Med Image Anal Lab, Madrid, Spain

[6] Hosp Quiron, Dept Neurol, Madrid, Spain

[7] Rey Juan Carlos Univ, Fac Hlth Sci, Aesthesiol Lab, Madrid, Spain

来源：

HEADACHE | 2011年 / 51卷 / 10期

关键词：

migraine; photophobia; light stimulation; defense mechanism; sensitization; VISUAL-EVOKED POTENTIALS; LUMINANCE CONTRAST; BOLD FMRI; STIMULATION; HABITUATION; MRI; EXCITABILITY; PHOTOPHOBIA; ACTIVATION; RESPONSES;

D O I：

10.1111/j.1526-4610.2011.02013.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background. The brain of migraineurs is hyperexcitable, particularly the occipital cortex, which is probably hypersensitive to light. Photophobia or hypersensitivity to light may be accounted for by an increased excitability of trigeminal, the visual pathways, and the occipital cortex.

引用

页码：1520 / 1528

页数：9

共 39 条

[1] Interictal cortical excitability in migraine:: A study using transcranial magnetic stimulation of motor and visual cortices [J].

Afra, J ;

Mascia, A ;

Gérard, P ;

de Noordhout, AM ;

Schoenen, J .

ANNALS OF NEUROLOGY, 1998, 44 (02) :209-215

[2] Visual evoked potentials during long periods of pattern-reversal stimulation in migraine [J].

Afra, J ;

Cecchini, AP ;

De Pasqua, V ;

Albert, A ;

Schoenen, J .

BRAIN, 1998, 121 :233-241

[3] Transcranial magnetic stimulation confirms hyperexcitability of occipital cortex in migraine [J].

Aurora, SK ;

Ahmad, BK ;

Welch, KMA ;

Bhardhwaj, P ;

Ramadan, NM .

NEUROLOGY, 1998, 50 (04) :1111-1114

[4] The occipital cortex is hyperexcitable in migraine: Experimental evidence [J].

Aurora, SK ;

Cao, Y ;

Bowyer, SM ;

Welch, KMA .

HEADACHE, 1999, 39 (07) :469-476

[5] Brain excitability in migraine: evidence from transcranial magnetic stimulation studies [J].

Aurora, SK ;

Welch, KMA .

CURRENT OPINION IN NEUROLOGY, 1998, 11 (03) :205-209

[6]

Bandettini PA, 1997, NMR BIOMED, V10, P197, DOI 10.1002/(SICI)1099-1492(199706/08)10:4/5<197::AID-NBM466>3.0.CO

[7]

2-S

[8]

Bandettini PA, 1997, HUM BRAIN MAPP, V5, P93

[9] Effects of repetitive transcranial magnetic stimulation on visual evoked potentials in migraine [J].

Bohotin, V ;

Fumal, A ;

Vandenheede, M ;

Gérard, P ;

Bohotin, C ;

de Noordhout, AM ;

Schoenen, J .

BRAIN, 2002, 125 :912-922

[10] Magnetoencephalographic fields from patients with spontaneous and induced migraine aura [J].

Bowyer, SM ;

Aurora, SK ;

Moran, JE ;

Tepley, N ;

Welch, KMA .

ANNALS OF NEUROLOGY, 2001, 50 (05) :582-587

← 1 2 3 4 →