Exophilin A, a new antibiotic from a marine microorganism Exophiala pisciphila

被引：51

作者：

Doshida, J ^{[1
]}

Hasegawa, H ^{[1
]}

Onuki, H ^{[1
]}

Shimidzu, N ^{[1
]}

机构：

[1] NIPPON SUISAN KAISHA LTD, CENT RES LAB, HACHIOJI, TOKYO 192, JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1996年 / 49卷 / 11期

关键词：

D O I：

10.7164/antibiotics.49.1105

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Exophilin A, a new antibacterial compound, was discovered in the culture of the marine microorganism Exophiala pisciphila NI10102, which was isolated from a marine sponge Mycale adhaerens. The absolute chemical structure of exophilin A was elucidated as a trimer of (3R,5R)-3,5-dihydroxydecanoic acid by spectroscopic methods and analyses of a degradative product. Exophilin A showed antimicrobial activity against Gram-positive bacteria.

引用

页码：1105 / 1109

页数：5

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