Current Status of Liver Transplantation for Hepatitis B Virus

被引:17
作者
Buchanan, Corinne [1 ]
Tran, Tram T. [1 ]
机构
[1] Univ Calif Los Angeles, Cedars Sinai Med Ctr, Geffen Sch Med, Ctr Liver Transplantat, Los Angeles, CA 90048 USA
关键词
Hepatitis B virus; Liver transplant; Hepatitis B immune globulin; Antiviral; HBcAb positivity; Genotype; ANTIBODY-POSITIVE DONORS; SEVERELY DECOMPENSATED CIRRHOSIS; LONG-TERM PROPHYLAXIS; ADEFOVIR DIPIVOXIL; LAMIVUDINE TREATMENT; IMMUNE GLOBULIN; E-ANTIGEN; ENTECAVIR THERAPY; CORE PROMOTER; UNITED-STATES;
D O I
10.1016/j.cld.2011.08.011
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The management of hepatitis B in liver transplantation has evolved significantly over the past 2 decades. Introduction of hepatitis B immune globulin and subsequently nucleos(t)ide analogues has revolutionized transplantation for hepatitis B virus (HBV), increasing survival for patients transplanted for this indication. With the availability of new and potent antivirals for HBV, the need for liver transplant should continue to decrease in the coming years. Moreover, the newer antivirals with high resistance barriers will allow effective long-term viral prophylaxis and therefore, prevention of recurrence.
引用
收藏
页码:753 / +
页数:13
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