Synthesis and X-ray diffraction data of 1-[N-(methyl)-(3,5-dimethylphenylamino)]methylnaphthalene

被引：2

作者：

Camargo, H. A. ^{[1
]}

Habran, N. M. ^{[1
]}

Henao, J. A. ^{[1
]}

Amado, D. F. ^{[2
]}

Kouznetsov, V. V. ^{[2
]}

机构：

[1] Univ Ind Santander, Escuela Quim, Grp Invest Quim Estruct GIQUE, Ctr Invest Biomol CIBIMOL,Fac Ciencias, Bucaramanga 678, Colombia

[2] Univ Ind Santander, Escuela Quim, Lab Quim Organ & Biomol LQOBio, Ctr Invest Biomol CIBIMOL,Fac Ciencias, Bucaramanga 678, Colombia

来源：

POWDER DIFFRACTION | 2011年 / 26卷 / 01期

关键词：

amines; X-ray powder diffraction; antifungal agents; POWDER; TERBINAFINE; RELIABILITY; CRITERION;

D O I：

10.1154/1.3540774

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

The 1-[N-(methyl)-(3,5-dimethylphenylamino)]methylnaphthalene (chemical formula C20H21N) was prepared by means of a condensation between alpha-naphthylaldehyde and 3,5-dimethylaniline in anhydrous ethanol to obtain the aldimine (1) which was reduced with NaBH4 to afford the 1-[N-(3,5-dimethylphenylamino)]methylnaphtalene (2), and finally, the compound (3) was obtained by N-alkylation reaction of (2) with methyl iodine (CH3I) and potassium carbonate (K2CO3) in acetone. Final compound (3) was purified by chromatographic column. The XRPD pattern for the new compound. 1-[N-(methyl)-(3,5-dimethylphenylamino)]methylnaphthalene, was obtained. This compound crystallizes in monoclinic system with space group P2(1)/a (No. 14) and relined unit-cell parameters a=13.260(4) angstrom, b=15.495(5) angstrom. c=7.719(5) angstrom. beta=90.19(6), and V=1586(1) angstrom(3). (C) 2011 International Centre or Diffraction Data. [DOI: 10.1154/1.3540774]

引用

页码：74 / 77

页数：4

共 14 条

[1] Powder pattern indexing with the dichotomy method [J].