共 49 条
Gold Nanoparticles-Decorated Silicon Nanowires as Highly Efficient Near-Infrared Hyperthermia Agents for Cancer Cells Destruction
被引:139
作者:
Su, Yuanyuan
[1
,2
,3
,4
]
Wei, Xinpan
[3
,4
]
Peng, Fei
[3
,4
]
Zhong, Yiling
[3
,4
]
Lu, Yimei
[3
,4
]
Su, Shao
[3
,4
]
Xu, Tingting
[1
,2
,3
,4
]
Lee, Shuit-Tong
[1
,2
]
He, Yao
[3
,4
]
机构:
[1] City Univ Hong Kong, Ctr Super Diamond & Adv Films COSDAF, Hong Kong, Hong Kong, Peoples R China
[2] City Univ Hong Kong, Dept Phys & Mat Sci, Hong Kong, Hong Kong, Peoples R China
[3] Soochow Univ, Inst Funct Nano & Soft Mat FUNSOM, Suzhou 215123, Peoples R China
[4] Soochow Univ, Jiangsu Key Lab Carbon Based Funct Mat & Devices, Suzhou 215123, Peoples R China
关键词:
Silicon nanowires;
hyperthermia agent;
cancer photothermal therapy;
near-infrared;
nanobioapplications;
SURFACE-PLASMON RESONANCE;
PHOTOTHERMAL THERAPY;
SILVER NANOPARTICLES;
CARBON NANOTUBES;
QUANTUM DOTS;
IN-VITRO;
NANOSPHERES;
ABSORPTION;
ABLATION;
NANORODS;
D O I:
10.1021/nl204203t
中图分类号:
O6 [化学];
学科分类号:
0703 ;
摘要:
Near-infrared (NIR) hyperthermia agents are of current interest because they hold great promise as highly efficacious tools for cancer photothermal therapy. Although various agents have been reported, a practical NIR hyperthermia agent is yet unavailable. Here, we present the first demonstration that silicon nanomaterials-based NIR hyperthermia agent, that is, gold nanoparticles-decorated silicon nanowires (AuNPs@SiNWs), is capable of high-efficiency destruction of cancer cells. AuNPs@SiNWs are found to possess strong optical absorbance in the NIR spectral window, producing sufficient heat under NIB. irradiation. AuNPs@SiNWs are explored as novel NIR hyperthermia agents for photothermal ablation of tumor cells. In particular, three different cancer cells treated with AuNPs@SiNWs were completely destructed within 3 min of NIR irradiation, demonstrating the exciting potential of AuNPs@SiNWs for NIR hyperthermia agents.
引用
收藏
页码:1845 / 1850
页数:6
相关论文
共 49 条