Current status of ribozymes as gene therapy agents for cancer

被引：18
作者：
Wright, L [1 ]
Kearney, P [1 ]
机构：
[1] St Vincents Hosp, Dept Hematol, Hematol Res Lab, Darlinghurst, NSW 2010, Australia
来源：
CANCER INVESTIGATION | 2001年 / 19卷 / 05期
关键词：
cancer; gene therapy; hammerhead ribozymes;
D O I：
10.1081/CNV-100103848
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
[No abstract available]
引用
收藏
页码：495 / 509
页数：15
相关论文
共 130 条
[1]   Inhibition of human immunodeficiency virus-1 (HIV-1) replication after transduction of granulocyte colony-stimulating factor-mobilized CD34(+) cells from HIV-1-infected donors using retroviral vectors containing anti-HIV-1 genes [J].
Bauer, G ;
Valdez, P ;
Kearns, K ;
Bahner, I ;
Wen, SF ;
Zaia, JA ;
Kohn, DB .
BLOOD, 1997, 89 (07) :2259-2267
[2]   CHEMICAL MODIFICATION OF HAMMERHEAD RIBOZYMES - CATALYTIC ACTIVITY AND NUCLEASE RESISTANCE [J].
BEIGELMAN, L ;
MCSWIGGEN, JA ;
DRAPER, KG ;
GONZALEZ, C ;
JENSEN, K ;
KARPEISKY, AM ;
MODAK, AS ;
MATULICADAMIC, J ;
DIRENZO, AB ;
HAEBERLI, P ;
SWEEDLER, D ;
TRACZ, D ;
GRIMM, S ;
WINCOTT, FE ;
THACKRAY, VG ;
USMAN, N .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (43) :25702-25708
[3]   Triple ribozyme-mediated down-regulation of the retinoblastoma gene [J].
Benedict, CM ;
Pan, WH ;
Loy, SE ;
Clawson, GA .
CARCINOGENESIS, 1998, 19 (07) :1223-1230
[4]  
BERKNER KL, 1988, BIOTECHNIQUES, V6, P616
[5]   CAN HAMMERHEAD RIBOZYMES BE EFFICIENT TOOLS TO INACTIVATE GENE-FUNCTION [J].
BERTRAND, E ;
PICTET, R ;
GRANGE, T .
NUCLEIC ACIDS RESEARCH, 1994, 22 (03) :293-300
[6]  
Bertrand E, 1997, RNA, V3, P75
[7]   Phase I trial of an antisense oligonucleotide OL(1)p53 in hematologic malignancies [J].
Bishop, MR ;
Iversen, PL ;
Bayever, E ;
Sharp, JG ;
Greiner, TC ;
Copple, BL ;
Ruddon, R ;
Zon, G ;
Spinolo, J ;
Arneson, M ;
Armitage, JO ;
Kessinger, A .
JOURNAL OF CLINICAL ONCOLOGY, 1996, 14 (04) :1320-1326
[8]  
BLAESE M, 1995, CANCER GENE THER, V2, P291
[9]  
BOS JL, 1989, CANCER RES, V49, P4682
[10]  
CAI DW, 1995, CANCER GENE THER, V2, P199
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