Research Progress of Raman Spectroscopy in Drug Analysis

被引:49
|
作者
Wang, Wen-ting [1 ]
Zhang, Hua [1 ]
Yuan, Yuan [2 ]
Guo, Ya [1 ]
He, Shi-xin [1 ]
机构
[1] Wanzhou Inst Food & Drug Control, Chongqing 404000, Peoples R China
[2] Xian Libang Pharmaceut Co Ltd, Xian 710075, Shaanxi, Peoples R China
来源
AAPS PHARMSCITECH | 2018年 / 19卷 / 07期
关键词
Raman spectroscopy; drug analysis; trace detection; qualitative and quantitative study; FOOD; IR;
D O I
10.1208/s12249-018-1135-8
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Raman spectroscopy is a spectroscopic analysis technique that enables rapid qualitative and quantitative detection based on inelastic collision and Raman scattering intensity. This review detailed the generation principle, instrument composition, influencing factors, and common classifications of Raman spectrum. Furthermore, it summarized and forecast the research progress of Raman spectroscopy in the field of drug analysis simultaneously over the past decade, including the identification of active pharmaceutical ingredients (APIs), qualitative and quantitative studies of pharmaceutical preparations, detection of illicit drugs, the identification of Chinese herbal medicines, and the combination with other technologies. The development of Raman spectroscopy in other fields is additionally summarized.
引用
收藏
页码:2921 / 2928
页数:8
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