Case Report: Role of an Iodinated Rectal Hydrogel Spacer, SpaceOAR Vue™, in the Context of Low-Dose-Rate Prostate Brachytherapy, for Enhanced Post-Operative Contouring to Aid in Accurate Implant Evaluation and Dosimetry

被引:3
作者
Gross, Andrew [1 ]
Yuan, Jiankui [1 ]
Spratt, Daniel [1 ]
Fredman, Elisha [1 ]
机构
[1] Univ Hosp Cleveland, Med Ctr, Seidman Canc Ctr, Dept Radiat Oncol, Cleveland, OH 44106 USA
来源
FRONTIERS IN ONCOLOGY | 2021年 / 11卷
关键词
prostate cancer; brachytherapy; radiation; SpaceOAR Vue; toxicity; EXTERNAL-BEAM RADIATION; LONG-TERM; ASCENDE-RT; RISK; CANCER; TOXICITY; TRIAL; INTERMEDIATE; BOOST; MEN;
D O I
10.3389/fonc.2021.810955
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
We present a case series of 13 consecutive patients with prostate cancer treated with low-dose-rate (LDR) brachytherapy, utilizing SpaceOAR Vue (TM), the recent iodinated iteration of the SpaceOAR (TM) hydrogel rectal spacer. Low- and favorable intermediate-risk patients receiving monotherapy and unfavorable intermediate- and high-risk patients undergoing a brachytherapy boost were included. Permanent brachytherapy can result in subacute and late rectal toxicity, and precise contouring of the anterior rectal wall and posterior aspect of the prostate is essential for accurate dosimetry to confirm a safe implant. Clearly visible on non-contrast CT imaging, SpaceOAR Vue (TM) can substantially aid in post-implant contouring and analysis. Not previously described in the literature in the context of LDR brachytherapy, we demonstrate the added clinical benefit of placing a well-visualized rectal spacer.
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页数:7
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