Perioperative Platelet Transfusion: Not All Platelet Products Are Created Equal

被引:3
作者
Fontaine, Magali J. [1 ]
Lasola, Jackline Joy Martin [1 ]
Henderson, Reney A. [2 ]
机构
[1] Univ Maryland, Sch Med, Dept Pathol, Baltimore, MD 21201 USA
[2] Univ Maryland, Dept Anesthesiol, Div Cardiothorac Anesthesia, Sch Med, 22 S Greene St, Baltimore, MD 21201 USA
关键词
Platelet component; Additive solution; Pathogen reduction; Temperature storage; Perioperative transfusion; Coagulation point of care testing; PATHOGEN INACTIVATION TREATMENT; ADDITIVE SOLUTIONS; CARDIAC-SURGERY; HEMOSTATIC FUNCTION; DIMETHYL-SULFOXIDE; ROOM-TEMPERATURE; WHOLE-BLOOD; STORAGE; PLASMA; CRYOPRESERVATION;
D O I
10.1007/s40140-022-00522-4
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Purpose of Review This review highlights current advances in platelet components for transfusion in the perioperative setting while explaining point of care methods to assess platelet function. Recent Findings The variety of options for platelet transfusion continues to grow, and despite all being under the umbrella of platelet components, nuances in the different products may introduce variability in responses that remain to be fully elucidated. Choices regarding platelet additive solutions, monitoring bacterial contamination, pathogen reduction technologies, and storage conditions, require a risk-benefit analysis of the specific needs of each patient and facility resources. This especially introduces challenges for perioperative platelet administration and monitoring of coagulation which is also discussed. Platelet products remain a mainstay for regulation of hemostatic stability. This review introduces key platelet product characteristics with implications for platelet choice as well as currently available technologies to monitor coagulation in the perioperative setting.
引用
收藏
页码:320 / 328
页数:9
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