IgG4-related pleural disease with aortitis and submandibular glands involvement successfully treated with corticosteroid: case-based review

被引：8

作者：

Okamoto, Shota ^{[1
]}

Tsuboi, Hiroto ^{[1
]}

Sato, Ryota ^{[1
]}

Terasaki, Mayu ^{[1
]}

Terasaki, Toshihiko ^{[1
]}

Toko, Hirofumi ^{[1
]}

Shimizu, Masaru ^{[1
]}

Honda, Fumika ^{[1
]}

Yagishita, Mizuki ^{[1
]}

Ohyama, Ayako ^{[1
]}

Kurata, Izumi ^{[1
]}

Abe, Saori ^{[1
]}

Takahashi, Hiroyuki ^{[1
]}

Osada, Atsumu ^{[1
]}

Hagiwara, Shinya ^{[1
]}

Kondo, Yuya ^{[1
]}

Matsumoto, Isao ^{[1
]}

Sumida, Takayuki ^{[1
]}

机构：

[1] Univ Tsukuba, Fac Med, Dept Internal Med, 1-1-1 Tennodai, Tsukuba, Ibaraki 3058575, Japan

来源：

RHEUMATOLOGY INTERNATIONAL | 2020年 / 40卷 / 10期

基金：

日本学术振兴会;

关键词：

IgG4-related disease; Pleural disease; Periaortitis; Submandibular gland; DIAGNOSTIC-CRITERIA; PLEURITIS; LUNG; STATEMENT;

D O I：

10.1007/s00296-020-04555-y

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

IgG4-related disease (IgG4-RD) is a fibro-inflammatory condition characterized by increased serum IgG4 level, infiltration of lymphocytes and IgG4-positive (IgG4(+)) plasma cells and fibrosis. It can occur in almost all organs, commonly affecting the pancreas, biliary tract, salivary and lacrimal glands and kidneys. However, reports of IgG4-RD accompanied by pathologically confirmed, IgG4-related pleural disease are scarce. Here, we present a case of a 64-year-old man with suspected malignant pleural mesothelioma based on imaging findings but finally diagnosed with IgG4-RD (including pleuritis, periaortitis and bilateral submandibular gland enlargement) based on a high serum IgG4 level and pleural histopathological findings such as lymphoplasmacytic infiltration including IgG4(+) plasma cells and fibrosis. Systemic corticosteroid therapy was effective at reducing serum IgG4, improving bilateral submandibular gland enlargement, and regressing pleural thickening and periaortic soft tissue. We also discuss clinical characteristics and pleural pathological features of previously reported cases with IgG4-related pleural disease based on a comprehensive literature review. Our case of IgG4-RD with pleura, aorta and submandibular gland involvement, pathologically confirmed by pleural specimen might be unique and very rare.

引用

页码：1725 / 1732

页数：8

共 35 条

[1] The clinical spectrum of IgG4-related disease [J].

Brito-Zeron, Pilar ;

Ramos-Casals, Manuel ;

Bosch, Xavier ;

Stone, John H. .

AUTOIMMUNITY REVIEWS, 2014, 13 (12) :1203-1210

[2] The diagnostic utility of serum IgG4 concentrations in IgG4-related disease [J].

Carruthers, Mollie N. ;

Khosroshahi, Arezou ;

Augustin, Tamara ;

Deshpande, Vikram ;

Stone, John H. .

ANNALS OF THE RHEUMATIC DISEASES, 2015, 74 (01) :14-18

[3] A Case Report of IgG4-Related Disease Clinically Mimicking Pleural Mesothelioma [J].

Choi, In Ho ;

Jang, Si-Hyong ;

Lee, Seungeun ;

Han, Joungho ;

Kim, Tae-Sung ;

Chung, Man-Pyo .

TUBERCULOSIS AND RESPIRATORY DISEASES, 2014, 76 (01) :42-45

[4] A Case of IgG4-Related Disease Presenting as Massive Pleural Effusion and Thrombophlebitis [J].

Choi, Jong Hyun ;

Sim, Jae Kyeom ;

Oh, Jee Youn ;

Lee, Eun Joo ;

Hur, Gyu Young ;

Lee, Seung Heon ;

Lee, Sung Yong ;

Kim, Je Hyeong ;

Lee, Sang Yeub ;

Shin, Chol ;

Shim, Jae Jeong ;

In, Kwang Ho ;

Kang, Kyung Ho ;

Min, Kyung Hoon .

TUBERCULOSIS AND RESPIRATORY DISEASES, 2014, 76 (04) :179-183

[5] IgG4-related pleural disease in a patient with a history of unknown origin acute pancreatitis: a case report and review of the literature [J].

Damas, F. ;

Ghysen, K. ;

Gester, F. ;

Heinen, V. ;

Duysinx, B. ;

Louis, R. ;

Guiot, J. .

ACTA CLINICA BELGICA, 2019, 74 (06) :465-468

[6] Consensus statement on the pathology of IgG4-related disease [J].

Deshpande, Vikram ;

Zen, Yoh ;

Chan, John K. ;

Yi, Eunhee E. ;

Sato, Yasuharu ;

Yoshino, Tadashi ;

Kloeppel, Guenter ;

Heathcote, J. Godfrey ;

Khosroshahi, Arezou ;

Ferry, Judith A. ;

Aalberse, Rob C. ;

Bloch, Donald B. ;

Brugge, William R. ;

Bateman, Adrian C. ;

Carruthers, Mollie N. ;

Chari, Suresh T. ;

Cheuk, Wah ;

Cornell, Lynn D. ;

Fernandez-Del Castillo, Carlos ;

Forcione, David G. ;

Hamilos, Daniel L. ;

Kamisawa, Terumi ;

Kasashima, Satomi ;

Kawa, Shigeyuki ;

Kawano, Mitsuhiro ;

Lauwers, Gregory Y. ;

Masaki, Yasufumi ;

Nakanuma, Yasuni ;

Notohara, Kenji ;

Okazaki, Kazuich ;

Ryu, Ji Kon ;

Saeki, Takako ;

Sahani, Dushyant V. ;

Smyrk, Thomas C. ;

Stone, James R. ;

Takahira, Masayuki ;

Webster, George J. ;

Yamamoto, Motohisa ;

Zamboni, Giuseppe ;

Umehara, Hisanori ;

Stone, John H. .

MODERN PATHOLOGY, 2012, 25 (09) :1181-1192

[7] Pathologies Associated with Serum IgG4 Elevation [J].

Ebbo, Mikael ;

Grados, Aurelie ;

Bernit, Emmanuelle ;

Vely, Frederic ;

Boucraut, Jose ;

Harle, Jean-Robert ;

Daniel, Laurent ;

Schleinitz, Nicolas .

INTERNATIONAL JOURNAL OF RHEUMATOLOGY, 2012, 2012

[8] IgG4-related disease can present as recurrent spontaneous hemothorax: a case report [J].

Fan, Junping ;

Feng, Ruie ;

Hou, Xiaomeng ;

Li, Ji ;

Sun, Xuefeng ;

Wang, Jinglan ;

Shi, Juhong ;

Wang, Mengzhao ;

Xu, Yan .

BMC PULMONARY MEDICINE, 2019, 19 (1)

[9] Intrathoracic Involvements of Immunoglobulin G4-Related Sclerosing Disease [J].

Fei, Yunyun ;

Shi, Juhong ;

Lin, Wei ;

Chen, Yu ;

Feng, Ruie ;

Wu, Qingjun ;

Gao, Xin ;

Xu, Wenbing ;

Zhang, Wen ;

Zhang, Xuan ;

Zhao, Yan ;

Zeng, Xiaofeng ;

Zhang, Fengchun .

MEDICINE, 2015, 94 (50)

[10] Immunoglobulin G4-related pleuritis - A case report [J].

Gajewska, Marta E. ;

Rychwicka-Kielek, Beata A. ;

Sorensen, Kathina ;

Kubik, Magdalena ;

Hilberg, Ole ;

Bendstrup, Elisabeth .

RESPIRATORY MEDICINE CASE REPORTS, 2016, 19 :18-20

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