Antioxidant and Cardioprotective Effects of N-Tyrosol in Myocardial Ischemia With Reperfusion in Rats

被引：0
作者：
Smolyakova, V. I.
Chernyshova, G. A.
Plotnkov, M. B.
Aliev, O. L.
Krasnov, E. A.
机构：
来源：
KARDIOLOGIYA | 2010年 / 50卷 / 11期
关键词：
n-tyrosol; myocardial ischemia; reperfusion; lipid peroxidation; antioxidants;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We demonstrated in experiments on rats with left coronary artery occlusion that intravenous administration of 20 mg/kg n-tyrosol during ischemia limited manifestations of oxidative stress in myocardial tissue during early post reperfusion period: content of diene and triene conjugates lowered 16 and 20%, respectively. This was associated with higher preservation of cardiomyocytes and reduction of the infarction zone.
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页码：47 / 49
页数：3
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