Successful Treatment of Paecilomyces variotii Peritonitis in a Liver Transplant Patient

被引：11

作者：

Polat, Meltem ^{[1
]}

Kara, Soner Sertan ^{[1
]}

Tapisiz, Anil ^{[1
]}

Demirtas, Zeliha ^{[2
]}

Sari, Sinan ^{[2
]}

Kalkanci, Ayse ^{[3
]}

Tezer, Hasan ^{[1
]}

Dalgic, Buket ^{[2
]}

机构：

[1] Gazi Univ, Sch Med, Dept Pediat Infect Dis, TR-06500 Ankara, Turkey

[2] Gazi Univ, Sch Med, Dept Pediat Gastroenterol, TR-06500 Ankara, Turkey

[3] Gazi Univ, Sch Med, Dept Microbiol, TR-06500 Ankara, Turkey

来源：

MYCOPATHOLOGIA | 2015年 / 179卷 / 3-4期

关键词：

Amphotericin B; Liver transplant; Paecilomyces variotii peritonitis; Voriconazole; VORICONAZOLE; COMBINATION;

D O I：

10.1007/s11046-014-9854-1

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Paecilomyces variotii has previously been reported as a causative pathogen for peritonitis in patients on continuous ambulatory peritoneal dialysis and shown to be usually sensitive to amphotericin B and resistant to voriconazole. We report the first case, to our knowledge, of P. variotii peritonitis in a liver transplant patient, which was unresponsive to initial liposomal amphotericin B (L-AmB) treatment and resolved dramatically after the addition of voriconazole. The present case provides evidence for the clinical and microbiological effectiveness of voriconazole combined with L-AmB in treating P. variotii peritonitis refractory to initial L-AmB treatment.

引用

页码：317 / 320

页数：4

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