Detection of Hg2+ by a FRET ratiometric fluorescent probe based on a novel pyrido[1,2-a]benzimidazole-rhodamine system

被引：61
作者：
Ge, Yanqing [1 ]
Liu, Aikun [1 ]
Ji, Ruixue [1 ]
Shen, Shili [1 ]
Cao, Xiaoqun [1 ]
机构：
[1] Taishan Med Univ, Sch Chem & Pharmaceut Engn, Tai An 271016, Shandong, Peoples R China
来源：
SENSORS AND ACTUATORS B-CHEMICAL | 2017年 / 251卷
关键词：
Pyrido[1,2-a]benzimidazole; FRET; Bioimaging; Fluorescent probe; Hg2+; ENERGY-TRANSFER; CHEMOSENSORS; IONS; CHEMODOSIMETER;
D O I：
10.1016/j.snb.2017.05.097
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A novel pyrido[1,2-a]benzimidazole-rhodamine ratiometric fluorescent probe TMUHg-3 for Hg2+ based on a fluorescence resonance energy transfer mechanism has been developed. In this system, the energy transfer efficiency is 87.3%. The probe can detect Hg2+ with a very low detection limit of 18.8 nM, and very high selectivity toward Hg2+. Furthermore, it can be used for imaging Hg2+ in living cells. (C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码：410 / 415
页数：6
相关论文
共 29 条
[1]   Detection of Hg2+ by a FRET ratiometric fluorescent probe based on a novel BODIPY-RhB system [J].
Cheng, Dandan ;
Zhao, Wenqi ;
Yang, Hongzhi ;
Huang, Ziping ;
Liu, Xingliang ;
Han, Aixia .
TETRAHEDRON LETTERS, 2016, 57 (24) :2655-2659
[2]   Rhodamine-pyrene conjugated chemosensors for ratiometric detection of Hg2+ ions: Different sensing behavior between a spirolactone and a spirothiolactone [J].
Chu, Kai-Hui ;
Zhou, Yi ;
Fang, Yuan ;
Wang, Li-Hong ;
Li, Ju-Ying ;
Yao, Cheng .
DYES AND PIGMENTS, 2013, 98 (03) :339-346
[3]   Dual Site-Controlled and Lysosome-Targeted Intramolecular Charge Transfer-Photoinduced Electron Transfer-Fluorescence Resonance Energy Transfer Fluorescent Probe for Monitoring pH Changes in Living Cells [J].
Dong, Baoli ;
Song, Xuezhen ;
Wang, Chao ;
Kong, Xiuqi ;
Tang, Yonghe ;
Lin, Weiying .
ANALYTICAL CHEMISTRY, 2016, 88 (07) :4085-4091
[4]   Energy transfer cassettes based on organic fluorophores: construction and applications in ratiometric sensing [J].
Fan, Jiangli ;
Hu, Mingming ;
Zhan, Peng ;
Peng, Xiaojun .
CHEMICAL SOCIETY REVIEWS, 2013, 42 (01) :29-43
[5]   Naphthalimide-Rhodamine based chemosensors for colorimetric and fluorescent sensing Hg2+ through different signaling mechanisms in corresponding solvent systems [J].
Fang, Yuan ;
Zhou, Yi ;
Li, Ju-Ying ;
Rui, Qing-Qing ;
Yao, Cheng .
SENSORS AND ACTUATORS B-CHEMICAL, 2015, 215 :350-359
[6]   The synthesis, characterization and optical properties of novel pyrido[1,2-a]benzimidazole derivatives [J].
Ge, Yan Qing ;
Jia, Jiong ;
Yang, He ;
Tao, Xu Tang ;
Wang, Jian Wu .
DYES AND PIGMENTS, 2011, 88 (03) :344-349
[7]   A simple pH fluorescent probe based on new fluorophore indolizine for imaging of living cells [J].
Ge, Yanqing ;
Liu, Aikun ;
Dong, Jian ;
Duan, Guiyun ;
Cao, Xiaoqun ;
Li, Fuyou .
SENSORS AND ACTUATORS B-CHEMICAL, 2017, 247 :46-52
[8]   A ratiometric fluorescent probe for sensing Cu2+ based on new imidazo[1,5-a]pyridine fluorescent dye [J].
Ge, Yanqing ;
Ji, Ruixue ;
Shen, Shili ;
Cao, Xiaoqun ;
Li, Fuyou .
SENSORS AND ACTUATORS B-CHEMICAL, 2017, 245 :875-881
[9]   A new pyrido[1,2-a] benzimidazole-rhodamine FRET system as an efficient ratiometric fluorescent probe for Cu2+ in living cells [J].
Ge, Yanqing ;
Zheng, Xiaoling ;
Ji, Ruixue ;
Shen, Shili ;
Cao, Xiaoqun .
ANALYTICA CHIMICA ACTA, 2017, 965 :103-110
[10]   Colorimetric and ratiometric fluorescent probe for hydrogen sulfide using a coumarin-pyronine FRET dyad with a large emission shift [J].
He, Longwei ;
Yang, Xueling ;
Liu, Yong ;
Lin, Weiying .
ANALYTICAL METHODS, 2016, 8 (45) :8022-8027
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