Impact of sinus rhythm maintenance on major adverse cardiac and cerebrovascular events after catheter ablation of atrial fibrillation: insights from AF frontier ablation registry

被引：5

作者：

Usuda, Keisuke ^{[1
]}

Kato, Takeshi ^{[1
]}

Tsuda, Toyonobu ^{[1
]}

Tada, Hayato ^{[1
]}

Niwa, Satoru ^{[1
]}

Usui, Soichiro ^{[1
]}

Sakata, Kenji ^{[1
]}

Hayashi, Kenshi ^{[1
]}

Furusho, Hiroshi ^{[1
]}

Kawashiri, Masaaki ^{[1
]}

Takamura, Masayuki ^{[1
]}

Otsuka, Takayuki ^{[2
]}

Suzuki, Shinya ^{[2
]}

Hirata, Akio ^{[3
]}

Murakami, Masato ^{[4
]}

Takami, Mitsuru ^{[5
]}

Kimura, Masaomi ^{[6
]}

Fukaya, Hidehira ^{[7
]}

Nakahara, Shiro ^{[8
]}

Shimizu, Wataru ^{[9
]}

Iwasaki, Yu-ki ^{[9
]}

Hayashi, Hiroshi ^{[9
]}

Harada, Tomoo ^{[10
]}

Nakajima, Ikutaro ^{[10
]}

Okumura, Ken ^{[11
]}

Koyama, Junjiroh ^{[11
]}

Tokuda, Michifumi ^{[12
]}

Yamane, Teiichi ^{[12
]}

Momiyama, Yukihiko ^{[13
]}

Tanimoto, Kojiro ^{[13
]}

Soejima, Kyoko ^{[14
]}

Nonoguchi, Noriko ^{[14
]}

Ejima, Koichiro ^{[15
]}

Hagiwara, Nobuhisa ^{[15
]}

Harada, Masahide ^{[16
]}

Sonoda, Kazumasa ^{[17
]}

Inoue, Masaru ^{[18
]}

Kumagai, Koji ^{[19
]}

Hayashi, Hidemori ^{[20
]}

Satomi, Kazuhiro ^{[21
]}

Yazaki, Yoshinao ^{[21
]}

Watari, Yuji ^{[22
]}

Arai, Masaru ^{[23
]}

Watanabe, Ryuta ^{[23
]}

Yokoyama, Katsuaki ^{[24
]}

Matsumoto, Naoya ^{[24
]}

Nagashima, Koichi ^{[23
]}

Okumura, Yasuo ^{[23
]}

机构：

[1] Kanazawa Univ, Grad Sch Med Sci, Dept Cardiovasc Med, Kanazawa, Ishikawa, Japan

[2] Cardiovasc Inst, Dept Cardiol, Tokyo, Japan

[3] Osaka Police Hosp, Cardiovasc Div, Osaka, Japan

[4] Shonan Kamakura Gen Hosp, Divison Cardiol, Kamakura, Kanagawa, Japan

[5] Saiseikai Nakatsu Hosp, Osaka, Japan

[6] Hirosaki Univ, Sch Med, Divison Cardiol Pulm Med & Nephrol, Aomori, Japan

[7] Kitasato Univ Hosp, Sagamihara, Kanagawa, Japan

[8] Dokkyo Med Univ, Saitama Med Ctr, Saitama, Japan

[9] Nippon Med Hosp, Tokyo, Japan

[10] St Marianna Univ, Sch Med Hosp, Kawasaki, Kanagawa, Japan

[11] Saiseikai Kumamoto Hosp, Kumamoto, Japan

[12] Tokyo Jikei Univ, Sch Med Hosp, Tokyo, Japan

[13] Natl Hosp Org, Tokyo Med Ctr, Tokyo, Japan

[14] Kyorin Univ Hosp, Tokyo, Japan

[15] Tokyo Womens Med Univ Hosp, Tokyo, Japan

[16] Fujita Univ, Hlth Hosp, Toyoake, Aichi, Japan

[17] Tokyo Rinkai Hosp, Tokyo, Japan

[18] Ishikawa Prefectural Cent Hosp, Kanazawa, Ishikawa, Japan

[19] Gunma Cardiovasc Ctr, Gunma, Japan

[20] Juntendo Univ, Tokyo, Japan

[21] Tokyo Med Univ Hosp, Tokyo, Japan

[22] Teikyo Univ, Tokyo, Japan

[23] Nihon Univ, Itabashi Hosp, Div Cardiol, Tokyo, Japan

[24] Nihon Univ Hosp, Dept Cardiol, Tokyo, Japan

来源：

HEART AND VESSELS | 2022年 / 37卷 / 02期

关键词：

Ablation; Atrial fibrillation; Stroke; Cardiovascular disease; Mortality; FOLLOW-UP; STROKE; RISK; MORTALITY; WARFARIN; MANAGEMENT; MECHANISMS; OUTCOMES; THERAPY; DEATH;

D O I：

10.1007/s00380-021-01929-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The impact of catheter ablation for atrial fibrillation (AF) on cardiovascular events and mortality is controversial. We investigated the impact of sinus rhythm maintenance on major adverse cardiac and cerebrovascular events after AF ablation from a Japanese multicenter cohort of AF ablation. We investigated 3326 consecutive patients (25.8% female, mean age 63.3 +/- 10.3 years) who underwent catheter ablation for AF from the atrial fibrillation registry to follow the long-term outcomes and use of anti coagulants after ablation (AF frontier ablation registry). The primary endpoint was a composite of stroke, transient ischemic attack, cardiovascular events, and all-cause death. During a mean follow-up of 24.0 months, 2339 (70.3%) patients were free from AF after catheter ablation, and the primary composite endpoint occurred in 144 (4.3%) patients. The AF nonrecurrence group had a significantly lower incidence of the primary endpoint (1.8 per 100 person-years) compared with the AF recurrence group (3.0 per 100 person-years, p = 0.003). The multivariate analysis revealed that freedom from AF (hazard ratio 0.61, 95% confidence interval 0.44-0.86, p = 0.005) was independently associated with the incidence of the composite event. In the multicenter cohort of AF ablation, sinus rhythm maintenance after catheter ablation was independently associated with lower rates of major adverse cardiac and cerebrovascular events.

引用

页码：327 / 336

页数：10

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