Axial resolution improvement by modulated deconvolution in Fourier domain optical coherence tomography

被引:14
作者
Bousi, Evgenia [1 ]
Pitris, Costas [1 ]
机构
[1] Univ Cyprus, KIOS Res Ctr Intelligent Syst & Networks, Dept Elect & Comp Engn, CY-1678 Nicosia, Cyprus
关键词
optical coherence tomography; resolution enhancement; medical and biological imaging;
D O I
10.1117/1.JBO.17.7.071307
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A novel technique for axial resolution improvement in Fourier domain optical coherence tomography (FDOCT) is presented. The technique is based on the deconvolution of modulated optical coherence tomography signals. In FDOCT, the real part of the Fourier transform of the interferogrann is modulated by a frequency which depends on the position of the interferogram in k space. A slight numerical k shift results in a different modulation frequency. By adding two shifted signals, beating can appear in the A-scan. When the amount of shifting is appropriately selected, deconvolution of the resulting depth profile, using suitable modulated kernels, yields a narrower resolution width. A resolution improvement by a factor of similar to 7 can be achieved without the need for a broader bandwidth light source. (C) 2012 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.JBO.17.7.071307]
引用
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页数:9
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