Cancer - How cells choose to die

被引：25
作者：
Lane, D [1 ]
机构：
[1] Univ Dundee, Ninewells Hosp & Med Sch, Dept Surg & Mol Oncol, Dundee DD1 9SY, Scotland
来源：
NATURE | 2001年 / 414卷 / 6859期
关键词：
D O I：
10.1038/35102132
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
11
引用
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页码：25 / +
页数：2
相关论文
共 11 条
[1]   p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells [J].
Chen, XB ;
Ko, LJ ;
Jayaraman, L ;
Prives, C .
GENES & DEVELOPMENT, 1996, 10 (19) :2438-2451
[2]   Caenorhabditis elegans p53:: Role in apoptosis, meiosis, and stress resistance [J].
Derry, WB ;
Putzke, AP ;
Rothman, JH .
SCIENCE, 2001, 294 (5542) :591-595
[3]   Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2 [J].
Gorina, S ;
Pavletich, NP .
SCIENCE, 1996, 274 (5289) :1001-1005
[4]   2 CELLULAR PROTEINS THAT BIND TO WILD-TYPE BUT NOT MUTANT P53 [J].
IWABUCHI, K ;
BARTEL, PL ;
LI, B ;
MARRACCINO, R ;
FIELDS, S .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (13) :6098-6102
[5]   Stimulation of p53-mediated transcriptional activation by the p53-binding proteins, 53BP1 and 53BP2 [J].
Iwabuchi, K ;
Li, B ;
Massa, HF ;
Trask, BJ ;
Date, T ;
Fields, S .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (40) :26061-26068
[6]  
Ludwig RL, 1996, MOL CELL BIOL, V16, P4952
[7]   Genetic determinants of p53-induced apoptosis and growth arrest [J].
Polyak, K ;
Waldman, T ;
He, TC ;
Kinzler, KW ;
Vogelstein, B .
GENES & DEVELOPMENT, 1996, 10 (15) :1945-1952
[8]   Increased apoptosis induction by 121F mutant p53 [J].
Saller, E ;
Tom, E ;
Brunori, M ;
Otter, M ;
Estreicher, A ;
Mack, DH ;
Iggo, R .
EMBO JOURNAL, 1999, 18 (16) :4424-4437
[9]   ASPP proteins specifically stimulate the apoptotic function of p53 [J].
Samuels-Lev, Y ;
O'Connor, DJ ;
Bergamaschi, D ;
Trigiante, G ;
Hsieh, JK ;
Zhong, S ;
Campargue, I ;
Naumovski, L ;
Crook, T ;
Lu, X .
MOLECULAR CELL, 2001, 8 (04) :781-794
[10]   Effects on normal fibroblasts and neuroblastoma cells of the activation of the p53 response by the nuclear export inhibitor leptomycin B [J].
Smart, P ;
Lane, EB ;
Lane, DP ;
Midgley, C ;
Vojtesek, B ;
Laín, S .
ONCOGENE, 1999, 18 (51) :7378-7386
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