Development and mechanical characterization of porous titanium bone substitutes

被引:142
作者
Barbas, A. [1 ,2 ]
Bonnet, A. -S. [1 ]
Lipinski, P. [1 ]
Pesci, R. [3 ]
Dubois, G. [2 ]
机构
[1] LaBPS ENIM, F-57078 Metz, France
[2] OBL Paris, F-92320 Chatillon, France
[3] LEM3 UMR CNRS 7239, ENSAM Arts & Metiers ParisTech, F-57070 Metz, France
关键词
Porous titanium; Implants; Bone substitute; Mechanical properties; Anisotropy; IMPLANTS; STRESS; TISSUE;
D O I
10.1016/j.jmbbm.2012.01.008
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Commercially Pure Porous Titanium (CPPTi) can be used for surgical implants to avoid the stress shielding effect due to the mismatch between the mechanical properties of titanium and bone. Most researchers in this area deal with randomly distributed pores or simple architectures in titanium alloys. The control of porosity, pore size and distribution is necessary to obtain implants with mechanical properties close to those of bone and to ensure their osseointegration. The aim of the present work was therefore to develop and characterize such a specific porous structure. First of all, the properties of titanium made by Selective Laser Melting (SLM) were characterized through experimental testing on bulk specimens. An elementary pattern of the porous structure was then designed to mimic the orthotropic properties of the human bone following several mechanical and geometrical criteria. Finite Element Analysis (PEA) was used to optimize the pattern. A porosity of 53% and pore sizes in the range of 860 to 1500 mu m were finally adopted. Tensile tests on porous samples were then carried out to validate the properties obtained numerically and identify the failure modes of the samples. Finally, FE elastoplastic analyses were performed on the porous samples in order to propose a failure criterion for the design of porous substitutes. (C) 2012 Elsevier Ltd. All rights reserved.
引用
收藏
页码:34 / 44
页数:11
相关论文
共 22 条
  • [1] [Anonymous], 1999, 58322 ISO
  • [2] A CONTINUOUS WAVE TECHNIQUE FOR THE MEASUREMENT OF THE ELASTIC PROPERTIES OF CORTICAL BONE
    ASHMAN, RB
    COWIN, SC
    VANBUSKIRK, WC
    RICE, JC
    [J]. JOURNAL OF BIOMECHANICS, 1984, 17 (05) : 349 - 361
  • [3] Castano M C, 2002, Int J Comput Dent, V5, P87
  • [4] Fabrication of porous titanium implants with biomechanical compatibility
    Chen, Y. J.
    Feng, B.
    Zhu, Y. P.
    Weng, J.
    Wang, J. X.
    Lu, X.
    [J]. MATERIALS LETTERS, 2009, 63 (30) : 2659 - 2661
  • [5] COWIN SC, 1989, BONE MECH, P102
  • [6] Cellular Ti-6Al-4V structures with interconnected macro porosity for bone implants fabricated by selective electron beam melting
    Heinl, Peter
    Mueller, Lenka
    Koerner, Carolin
    Singer, Robert F.
    Mueller, Frank A.
    [J]. ACTA BIOMATERIALIA, 2008, 4 (05) : 1536 - 1544
  • [7] Structural, mechanical and in vitro characterization of individually structured Ti-6Al-4V produced by direct laser forming
    Hollander, DA
    von Walter, M
    Wirtz, T
    Sellei, R
    Schmidt-Rohlfing, B
    Paar, O
    Erli, HJ
    [J]. BIOMATERIALS, 2006, 27 (07) : 955 - 963
  • [8] The long-term clinical relevance of calcar atrophy caused by stress shielding in total hip arthroplasty - A 10-year, prospective, randomized study
    Karachalios, T
    Tsatsaronis, C
    Efraimis, G
    Papadelis, P
    Lyritis, G
    Diakoumopoulos, G
    [J]. JOURNAL OF ARTHROPLASTY, 2004, 19 (04) : 469 - 475
  • [9] Low stiffness porous Ti structures for load-bearing implants
    Krishna, B. Vamsi
    Bose, Susmita
    Bandyopadhyay, Amit
    [J]. ACTA BIOMATERIALIA, 2007, 3 (06) : 997 - 1006
  • [10] Porous Ti6Al4V scaffold directly fabricating by rapid prototyping:: Preparation and in vitro experiment
    Li, JP
    de Wijn, JR
    Van Blitterswijk, CA
    de Groot, K
    [J]. BIOMATERIALS, 2006, 27 (08) : 1223 - 1235