Cardiovascular Risk in Diabetes Mellitus: Complication of the Disease or of Antihyperglycemic Medications

被引：32

作者：

Alvarez, C. A. ^{[1
,2
]}

Lingvay, I. ^{[3
]}

Vuylsteke, V. ^{[1
]}

Koffarnus, R. L. ^{[1
]}

McGuire, D. K. ^{[3
]}

机构：

[1] Texas Tech Univ, Hlth Sci Ctr, Dallas, TX 75235 USA

[2] Univ Texas Southwestern, Dallas, TX USA

[3] Univ Texas SW Med Ctr Dallas, Dallas, TX 75390 USA

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2015年 / 98卷 / 02期

基金：

美国国家卫生研究院;

关键词：

INTIMA-MEDIA THICKNESS; IMPAIRED GLUCOSE-TOLERANCE; INADEQUATE GLYCEMIC CONTROL; BLOOD-PRESSURE; HEART-FAILURE; ENDOTHELIAL FUNCTION; DOUBLE-BLIND; VASCULAR COMPLICATIONS; CLINICAL-IMPLICATIONS; NONDIABETIC PATIENTS;

D O I：

10.1002/cpt.143

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Cardiovascular disease is the principal complication and the leading cause of death for patients with diabetes (DM). The efficacy of antihyperglycemic treatments on cardiovascular disease risk remains uncertain. Cardiovascular risk factors are affected by antihyperglycemic medications, as are many intermediate markers of cardiovascular disease. Here we summarize the evidence assessing the cardiovascular effects of antihyperglycemic medications with regard to risk factors, intermediate markers of disease, and clinical outcomes.

引用

页码：145 / 161

页数：17

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