Synthesis of a water-soluble ytterbium porphyrin-bovine serum albumin conjugate

被引:12
|
作者
Chudinov, AV
Rumyantseva, VD
Lobanov, AV
Chudinova, GK
Stomakhin, AA
Mironov, AF
机构
[1] Russian Acad Sci, VA Engelhardt Mol Biol Inst, Moscow 117984, Russia
[2] Lomonosov State Acad Fine Chem Technol, Moscow 119571, Russia
[3] Russian Acad Sci, Res Ctr Photochem, Moscow, Russia
基金
俄罗斯基础研究基金会;
关键词
conjugates; fluorescence; near IR region; serum albumin; ytterbium porphyrins;
D O I
10.1023/B:RUBI.0000015779.37503.8d
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The ytterbium complex of 5,10,15,20-tetrakis(4-carboxyphenyl)porphyrin was synthesized as an IR-fluorescent label and covalently bound to bovine serum albumin. The resulting, conjugate fluoresces at 985 nm and is of interest for use in IR-fluorescent tumor diagnostic, immunoassay, and energy transfer studies.
引用
收藏
页码:89 / 93
页数:5
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