Recent progress in design and preparation of glucose-responsive insulin delivery systems

被引：84

作者：

Shen, Di ^{[1
]}

Yu, Haojie ^{[1
]}

Wang, Li ^{[1
]}

Khan, Amin ^{[1
]}

Haq, Fazal ^{[1
]}

Chen, Xiang ^{[1
]}

Huang, Qiao ^{[1
]}

Teng, Lisong ^{[2
]}

机构：

[1] Zhejiang Univ, State Key Lab Chem Engn, Coll Chem & Biol Engn, Hangzhou 310027, Peoples R China

[2] Zhejiang Univ, Affiliated Hosp 1, Oncol Surg & Canc Ctr, Hangzhou 310003, Zhejiang, Peoples R China

来源：

JOURNAL OF CONTROLLED RELEASE | 2020年 / 321卷

关键词：

Glucose-responsive compounds; Controlling release; Insulin delivery; MESOPOROUS SILICA NANOPARTICLES; BORONATE AFFINITY-CHROMATOGRAPHY; HAMMETT SUBSTITUENT CONSTANTS; ORAL DELIVERY; CONTROLLED-RELEASE; DIABETES-MELLITUS; CONCANAVALIN-A; PHENYLBORONIC ACID; SENSITIVE VESICLES; ASPERGILLUS-NIGER;

D O I：

10.1016/j.jconrel.2020.02.014

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Diabetes, as a global threat nowadays, causes the wide usage of exogenous insulin. Subcutaneous injection is the traditional insulin administration in the diabetes treatments and is inconvenient and painful, which results in potential side effects of hypoglycemia. Scientists have made great efforts to develop alternatives. As the promising solutions, smart insulin delivery systems fabricated with glucose- responsive compounds attract considerable attention in the field of diabetes treatments. This review discusses the classifications, properties, response mechanisms of the glucose-responsive compounds, glucose oxidase and concanavalin A and recent progress of glucose-responsive insulin delivery systems.

引用

页码：236 / 258

页数：23

共 184 条

[1] Alberti KGMM, 1998, DIABETIC MED, V15, P539, DOI 10.1002/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO
[2] 2-S
[3] Solid lipid nanoparticles as a drug delivery system for peptides and proteins
Almeida, Antonio J.
Souto, Eliana
[J]. ADVANCED DRUG DELIVERY REVIEWS, 2007, 59 (06) : 478 - 490
[4] Pharmacological and toxicological assessment of innovative self-assembled polymeric micelles as powders for insulin pulmonary delivery
Andrade, Fernanda
Fonte, Pedro
Costa, Ana
Reis, Cassilda Cunha
Nunes, Rute
Almeida, Andreia
Ferreira, Domingos
Oliva, Mireia
Sarmento, Bruno
[J]. NANOMEDICINE, 2016, 11 (17) : 2305 - 2317
[5] [Anonymous], NEW ENGL J MED
[6] [Anonymous], 2013, ANGEW CHEM-GER EDIT, DOI DOI 10.1002/ANGE
[7] Regulated basal and bolus insulin release from glucose-responsive core-shell microspheres based on concanavalin A-sugar affinity
Bai, Meirong
He, Jing
Kang, Liangfa
Nie, Jun
Yin, Ruixue
[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 113 : 889 - 899
[8] Glucose oxidase - An overview
Bankar, Sandip B.
Bule, Mahesh V.
Singhal, Rekha S.
Ananthanarayan, Laxmi
[J]. BIOTECHNOLOGY ADVANCES, 2009, 27 (04) : 489 - 501
[9] A kinetic study on air oxidation of glucose catalyzed by immobilized glucose oxidase for production of calcium gluconate
Bao, J
Furumoto, K
Fukunaga, K
Nakao, K
[J]. BIOCHEMICAL ENGINEERING JOURNAL, 2001, 8 (02) : 91 - 102
[10] Effectiveness of Sensor-Augmented Insulin-Pump Therapy in Type 1 Diabetes
Bergenstal, Richard M.
Tamborlane, William V.
Ahmann, Andrew
Buse, John B.
Dailey, George
Davis, Stephen N.
Joyce, Carol
Peoples, Tim
Perkins, Bruce A.
Welsh, John B.
Willi, Steven M.
Wood, Michael A.
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2010, 363 (04) : 311 - 320

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