Buprenorphine in the Treatment of Chronic Pain

被引：16
作者：
Rudolf, Gregory D. [1 ]
机构：
[1] Swedish Pain Serv, 600 Broadway,Suite 530, Seattle, WA 98122 USA
来源：
PHYSICAL MEDICINE AND REHABILITATION CLINICS OF NORTH AMERICA | 2020年 / 31卷 / 02期
关键词：
Buprenorphine; Opioids; Chronic pain; TRANSDERMAL BUPRENORPHINE; SUBLINGUAL BUPRENORPHINE; EFFICACY; HYPERALGESIA; INHIBITION; ANALGESIA; AGONIST; SAFETY; ABUSE; TRIAL;
D O I：
10.1016/j.pmr.2020.02.001
中图分类号：
R49 [康复医学];
学科分类号：
100215 ;
摘要：
The burden of chronic pain in the United States is staggering. Concurrently, the problems associated with use of opioids for treatment of chronic pain have been prominently scrutinized in recent years. Buprenorphine is an opioid that is available for treatment of both chronic pain and opioid use disorder. Its use for chronic pain has been hampered by various factors including complex and often misunderstood pharmacology, challenges to transition and induction to buprenorphine from other opioids, provider perceptions around the legality of prescribing sublingual buprenorphine for pain, and insurance coverage limitations. This article reviews the pharmacology and clinical effectiveness of buprenorphine in the context of chronic pain treatment.
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收藏
页码：195 / +
页数：11
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