Multicentric Castleman's disease in two cases

被引:8
|
作者
Sharma, Rajni [1 ]
Seth, Rachna [1 ]
Thavaraj, V. [1 ]
Bagga, A. [1 ]
Kabra, S. K. [1 ]
Karak, A. K. [2 ]
Atri, S. [2 ]
机构
[1] All India Inst Med Sci, Dept Pediat, New Delhi 110029, India
[2] All India Inst Med Sci, Dept Pathol, New Delhi 110029, India
关键词
multicentric castleman's disease; Lymphoproliferative disorder; asplenia;
D O I
10.1007/s12098-007-0210-z
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Castleman's disease is an atypical lymphoproliferative disorder having two types of presentation- the localized and the multicentric form. The localized form presents as a slowly growing mass with a relatively benign course. Multicentric Castleman's disease has a more aggressive clinical course with diffuse lymph node enlargement and systemic illness. It is rarely seen in childhood and only thirteen cases have been reported in literature. This is the first report of 2 cases from the Indian subcontinent with a maximum follow-up of 44 months one of whom had asplenia.
引用
收藏
页码:1116 / 1120
页数:5
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