Sterically controlled C-H alkenylation of pyrroles and thiophenes

被引：13

作者：

Kang, Eunsu ^{[1
]}

Jeon, Ju Eun ^{[1
]}

Jeong, Siyeon ^{[1
]}

Kim, Hyun Tae ^{[1
]}

Joo, Jung Min ^{[1
]}

机构：

[1] Pusan Natl Univ, Inst Funct Mat, Dept Chem & Chem, Busan 46241, South Korea

来源：

CHEMICAL COMMUNICATIONS | 2021年 / 57卷 / 89期

基金：

新加坡国家研究基金会;

关键词：

BOND FUNCTIONALIZATION; LIGAND; ANNULATION;

D O I：

10.1039/d1cc04378a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Pd-catalyzed C-H alkenylations targeting the least hindered position of N-alkyl pyrroles and 3-substituted thiophenes, as opposed to electronically controlled approaches, are developed. The steric demand and stable bidentate binding mode of the pyrazolonaphthyridine ligand are key to the success of these sterically controlled alkenylations using oxygen as an oxidant.

引用

页码：11791 / 11794

页数：4

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