Endothelin receptor antagonist bosentan improves the dermal sclerosis in a patient with systemic sclerosis

被引:3
|
作者
Nishibu, Akiko [1 ,2 ]
Sakai, Erika [1 ]
Oyama, Noritaka [1 ]
Yamamoto, Toshiyuki [1 ]
机构
[1] Fukushima Med Univ, Dept Dermatol, Fukushima, Japan
[2] Kanazawa Med Univ, Dept Dermatol, Kanazawa, Ishikawa, Japan
关键词
bosentan; endothelin; systemic sclerosis; DIGITAL ULCERS;
D O I
10.1111/j.1440-0960.2010.00719.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
We report a case of systemic sclerosis with interstitial pneumonia and severe pulmonary hypertension treated with bosentan, an endothelin receptor antagonist. Within a short period of administration of the bosentan the skin sclerosis improved.
引用
收藏
页码:E32 / E33
页数:2
相关论文
共 50 条
  • [31] Improvement of plasma endothelin-1 and nitric oxide in patients with systemic sclerosis by bosentan therapy
    Kawashiri, Shin-ya
    Ueki, Yukitaka
    Terada, Kaoru
    Yamasaki, Satoshi
    Aoyagi, Kiyoshi
    Kawakami, Atsushi
    RHEUMATOLOGY INTERNATIONAL, 2014, 34 (02) : 221 - 225
  • [32] Improvement of plasma endothelin-1 and nitric oxide in patients with systemic sclerosis by bosentan therapy
    Shin-ya Kawashiri
    Yukitaka Ueki
    Kaoru Terada
    Satoshi Yamasaki
    Kiyoshi Aoyagi
    Atsushi Kawakami
    Rheumatology International, 2014, 34 : 221 - 225
  • [33] Bosentan for digital ulcers in patients with systemic sclerosis
    Nagai, Yayoi
    Hasegawa, Michiko
    Tago, Osamu
    Ishikawa, Osamu
    JOURNAL OF DERMATOLOGY, 2010, 37 : 68 - 68
  • [34] Bosentan Improves Skin Perfusion of Hands in Patients with Systemic Sclerosis with Pulmonary Arterial Hypertension
    Rosato, Edoardo
    Molinaro, Ilenia
    Borghese, Federica
    Rossi, Carmelina
    Pisarri, Simonetta
    Salsano, Felice
    JOURNAL OF RHEUMATOLOGY, 2010, 37 (12) : 2531 - 2539
  • [35] A clinical comparison of an endothelin receptor antagonist and phosphodiesterase type 5 inhibitors for treating digital ulcers of systemic sclerosis
    Chang, Sung Hae
    Jun, Jae Bum
    Lee, Yun Jong
    Kang, Tae Young
    Moon, Ki Won
    Ju, Ji Hyeon
    Kang, Seong Wook
    Choi, In Ah
    Park, Yong-Beom
    Lee, Seung Geun
    Lee, Shin-Seok
    Heo, Nam Hun
    Lee, Eun Bong
    RHEUMATOLOGY, 2021, 60 (12) : 5814 - 5819
  • [36] Long-Term Treatment With Endothelin Receptor Antagonist Increases Peripheral Blood Perfusion In Systemic Sclerosis Patients
    Cutolo, Maurizio
    Ruaro, Barbara
    Bernero, Elena
    Ravera, Francesca
    Zampogna, Giuseppe
    Alessandri, Elisa
    Smith, Vanessa
    Sulli, Alberto
    ARTHRITIS AND RHEUMATISM, 2013, 65 : S1102 - S1102
  • [37] Successful Treatment of Systemic-Sclerosis-Related Digital Ulcers with a Selective Endothelin Type A Receptor Antagonist (Sitaxentan)
    Gholam, P.
    Sehr, T.
    Enk, A.
    Hartmann, M.
    DERMATOLOGY, 2009, 219 (02) : 171 - 173
  • [38] Effect of the dual endothelin receptor antagonist bosentan on Raynaud's phenomenon secondary to systemic sclerosis: a double-blind prospective, randomized, placebo-controlled pilot study
    Nguyen, Van Anh
    Eisendle, Klaus
    Gruber, Ingrid
    Hugl, Beate
    Reider, Daniela
    Reider, Norbert
    RHEUMATOLOGY, 2010, 49 (03) : 583 - 587
  • [39] Low-dose combination therapy of severe digital ulcers in diffuse progressive systemic sclerosis with the endothelin-1 receptor antagonist bosentan and the phosphodiesterase V inhibitor sildenafil
    Ambach, Andreas
    Seo, Won
    Bonnekoh, Bernd
    Gollnick, Harald
    JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2009, 7 (10): : 888 - 891
  • [40] Development of an Efficient Alternative Synthesis of the Endothelin Receptor Antagonist Bosentan
    Panchal, Jigar
    Misra, Namita
    Devi, Meenu
    Sharma, Ashima
    Jain, Sonika
    Jain, Pankaj
    Dwivedi, Jaya
    Sharma, Swapnil
    ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 2023, 55 (05) : 404 - 410